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Vestronidase Alfa-vjbk Injection

Massachusetts rates for HCPCS J3397 · Mepsevii

Injection, vestronidase alfa-vjbk, 1 mg

Rates data updated July 2026.

How much does Mepsevii (vestronidase alfa) cost?

$288per mg

Typical negotiated rate. In Massachusetts, July 2026.

Insurers have agreed to pay about $288 for each mg of this drug. The price depends on where it is billed: about $288 from a physician practice, and about $355 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

Work out the cost of a dose

This drug is priced per mg. Enter the amount given to see what insurers have agreed to pay for it.

mg
In a doctor's office or clinic
$288
At a hospital outpatient department
$355

The same drug, in the same amount, costs 23% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$288$288 to $288
FacilityA hospital or hospital-owned outpatient department$355$324 to $468

How much rates vary

Facilitymedian $355 · 10th to 90th $288 to $676Professionalmedian $288 · 10th to 90th $288 to $468
$200$500$1K$2K$5Kfacility $355professional $288

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$288.40
Median
$467.74
Typical High
$676.08
Aetna
Setting
Professional
Modifier
Global
Typical Low
$288.40
Median
$288.40
Typical High
$288.40
AllWays Health Partners
Setting
Facility
Modifier
Global
Typical Low
$218.78
Median
$218.78
Typical High
$1,412.54
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$281.84
Median
$281.84
Typical High
$426.58
BCBS
Setting
Facility
Modifier
Global
Typical Low
$323.59
Median
$323.59
Typical High
$645.65
Cigna
Setting
Facility
Modifier
Global
Typical Low
$371.54
Median
$602.56
Typical High
$1,258.93
Cigna
Setting
Professional
Modifier
Global
Typical Low
$288.40
Median
$288.40
Typical High
$331.13
Fallon Health
Setting
Facility
Modifier
Global
Typical Low
$281.84
Median
$436.52
Typical High
$7,079.46
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$288.40
Median
$288.40
Typical High
$478.63
Mass General Brigham
Setting
Facility
Modifier
Global
Typical Low
$218.78
Median
$218.78
Typical High
$1,412.54
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$281.84
Median
$281.84
Typical High
$426.58
United
Setting
Facility
Modifier
Global
Typical Low
$281.84
Median
$281.84
Typical High
$602.56
United
Setting
Professional
Modifier
Global
Typical Low
$281.84
Median
$288.40
Typical High
$302.00

Where Massachusetts sits

The same service costs 1.7 times more in Colorado than in North Carolina. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Massachusetts· 13th of 51

$288

CO $468NC $275

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.