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Vestronidase Alfa-vjbk Injection

Colorado rates for HCPCS J3397 · Mepsevii

Injection, vestronidase alfa-vjbk, 1 mg

Rates data updated July 2026.

How much does Mepsevii (vestronidase alfa) cost?

$468per mg

Typical negotiated rate. In Colorado, July 2026.

Insurers have agreed to pay about $468 for each mg of this drug. The price depends on where it is billed: about $269 from a physician practice, and about $550 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

Work out the cost of a dose

This drug is priced per mg. Enter the amount given to see what insurers have agreed to pay for it.

mg
In a doctor's office or clinic
$269
At a hospital outpatient department
$550

The same drug, in the same amount, costs 104% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$269$269 to $288
FacilityA hospital or hospital-owned outpatient department$550$457 to $708

How much rates vary

Facilitymedian $550 · 10th to 90th $269 to $1,072Professionalmedian $269 · 10th to 90th $269 to $288
$200$500$1Kfacility $550professional $269

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$269.15
Median
$588.84
Typical High
$1,148.15
Aetna
Setting
Professional
Modifier
Global
Typical Low
$269.15
Median
$269.15
Typical High
$275.42
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$426.58
Median
$549.54
Typical High
$1,071.52
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$269.15
Median
$288.40
Typical High
$288.40
Cigna
Setting
Facility
Modifier
Global
Typical Low
$288.40
Median
$288.40
Typical High
$288.40
Cigna
Setting
Professional
Modifier
Global
Typical Low
$288.40
Median
$288.40
Typical High
$288.40
Denver HMP
Setting
Facility
Modifier
Global
Typical Low
$263.03
Median
$295.12
Typical High
$371.54
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$371.54
Median
$371.54
Typical High
$371.54
Select Health
Setting
Facility
Modifier
Global
Typical Low
$323.59
Median
$323.59
Typical High
$323.59
Select Health
Setting
Professional
Modifier
Global
Typical Low
$302.00
Median
$302.00
Typical High
$302.00
United
Setting
Facility
Modifier
Global
Typical Low
$302.00
Median
$457.09
Typical High
$831.76
United
Setting
Professional
Modifier
Global
Typical Low
$281.84
Median
$281.84
Typical High
$281.84

Where Colorado sits

The same service costs 1.7 times more in Colorado than in North Carolina. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Colorado· 1st of 51

$468

CO $468NC $275

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.