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Plasminogen Injection

Tennessee rates for HCPCS J2998 · Ryplazim

Injection, plasminogen, human-tvmh, 1 mg

Rates data updated October 2026.

How much does Ryplazim (plasminogen) cost?

$39.81per mg

Typical physician fee. In Tennessee, October 2026.

Insurers have agreed to pay about $39.81 for each mg of this drug. Most negotiated rates run $39.81 to $44.67.

Work out the cost of a dose

This drug is priced per mg. Enter the amount given to see what insurers have agreed to pay for it.

mg
In a doctor's office or clinic
$39.81

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $50 · 10th to 90th $45 to $72Professionalmedian $40 · 10th to 90th $40 to $41
$50$100facility $50professional $40

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$39.81
Median
$50.12
Typical High
$60.26
Aetna
Setting
Professional
Modifier
None
Typical Low
$39.81
Median
$39.81
Typical High
$39.81
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$19.95
Median
$19.95
Typical High
$19.95
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$7.94
Median
$7.94
Typical High
$7.94
Aetna
Setting
Professional
Modifier
55 · Aftercare only
Typical Low
$6.03
Median
$6.03
Typical High
$6.03
Aetna
Setting
Professional
Modifier
56 · Pre-op care only
Typical Low
$3.98
Median
$3.98
Typical High
$3.98
BCBS Tennessee
Setting
Professional
Modifier
None
Typical Low
$39.81
Median
$39.81
Typical High
$39.81
Cigna
Setting
Facility
Modifier
None
Typical Low
$44.67
Median
$50.12
Typical High
$72.44
Cigna
Setting
Professional
Modifier
None
Typical Low
$40.74
Median
$40.74
Typical High
$40.74
United
Setting
Professional
Modifier
None
Typical Low
$39.81
Median
$39.81
Typical High
$40.74

Where Tennessee sits

The same service costs 1.8 times more in Alaska than in Nebraska. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Tennessee· 48th of 51

$39.81

AK $64.57NE $36.31

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.