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Plasminogen Injection

Nebraska rates for HCPCS J2998 · Ryplazim

Injection, plasminogen, human-tvmh, 1 mg

Rates data updated October 2026.

How much does Ryplazim (plasminogen) cost?

$36.31per mg

Typical negotiated rate. In Nebraska, October 2026.

Insurers have agreed to pay about $36.31 for each mg of this drug. The price depends on where it is billed: about $36.31 from a physician practice, and about $33.88 from a hospital or other facility.

Work out the cost of a dose

This drug is priced per mg. Enter the amount given to see what insurers have agreed to pay for it.

mg
In a doctor's office or clinic
$36.31
At a hospital outpatient department
$33.88

The same drug, in the same amount, costs 7% less at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$36.31$33.88 to $39.81
FacilityA hospital or hospital-owned outpatient department$33.88$30.90 to $33.88

How much rates vary

Facilitymedian $34 · 10th to 90th $28 to $48Professionalmedian $36 · 10th to 90th $32 to $44
$50$100facility $34professional $36

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$38.02
Median
$47.86
Typical High
$75.86
Aetna
Setting
Professional
Modifier
None
Typical Low
$38.02
Median
$38.02
Typical High
$38.02
BCBS Nebraska
Setting
Facility
Modifier
None
Typical Low
$28.18
Median
$33.88
Typical High
$33.88
BCBS Nebraska
Setting
Professional
Modifier
None
Typical Low
$32.36
Median
$33.88
Typical High
$33.88
Cigna
Setting
Professional
Modifier
None
Typical Low
$33.11
Median
$40.74
Typical High
$41.69
Medica
Setting
Facility
Modifier
None
Typical Low
$36.31
Median
$66.07
Typical High
$162.18
Medica
Setting
Professional
Modifier
None
Typical Low
$36.31
Median
$36.31
Typical High
$43.65
United
Setting
Professional
Modifier
None
Typical Low
$38.02
Median
$39.81
Typical High
$47.86

Where Nebraska sits

The same service costs 1.8 times more in Alaska than in Nebraska. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Nebraska· 51st of 51

$36.31

AK $64.57NE $36.31

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.