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Plasminogen Injection

Kentucky rates for HCPCS J2998 · Ryplazim

Injection, plasminogen, human-tvmh, 1 mg

Rates data updated July 2026.

How much does Ryplazim (plasminogen) cost?

$35.48per mg

Typical negotiated rate. In Kentucky, July 2026.

Insurers have agreed to pay about $35.48 for each mg of this drug. The price depends on where it is billed: about $38.02 from a physician practice, and about $35.48 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

Work out the cost of a dose

This drug is priced per mg. Enter the amount given to see what insurers have agreed to pay for it.

mg
In a doctor's office or clinic
$38.02
At a hospital outpatient department
$35.48

The same drug, in the same amount, costs 7% less at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$38.02$30.20 to $38.02
FacilityA hospital or hospital-owned outpatient department$35.48$35.48 to $38.02

How much rates vary

Facilitymedian $35 · 10th to 90th $35 to $76Professionalmedian $38 · 10th to 90th $30 to $40
$50$100$200facility $35professional $38

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$38.02
Median
$38.02
Typical High
$81.28
Aetna
Setting
Professional
Modifier
Global
Typical Low
$38.02
Median
$38.02
Typical High
$39.81
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$33.88
Median
$35.48
Typical High
$67.61
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$30.20
Median
$30.20
Typical High
$30.20
CareSource
Setting
Facility
Modifier
Global
Typical Low
$41,686.94
Median
$52,480.75
Typical High
$63,095.73
CareSource
Setting
Professional
Modifier
Global
Typical Low
$40.74
Median
$40.74
Typical High
$40.74
Cigna
Setting
Facility
Modifier
Global
Typical Low
$45.71
Median
$45.71
Typical High
$141.25
Cigna
Setting
Professional
Modifier
Global
Typical Low
$40.74
Median
$213.80
Typical High
$213.80
United
Setting
Professional
Modifier
Global
Typical Low
$39.81
Median
$39.81
Typical High
$39.81

Where Kentucky sits

The same service costs 1.9 times more in Colorado than in North Carolina. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Kentucky· 50th of 51

$35.48

CO $66.07NC $33.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.