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Plasminogen Injection

Arizona rates for HCPCS J2998 · Ryplazim

Injection, plasminogen, human-tvmh, 1 mg

Rates data updated October 2026.

How much does Ryplazim (plasminogen) cost?

$56.23per mg

Typical negotiated rate. In Arizona, October 2026.

Insurers have agreed to pay about $56.23 for each mg of this drug. The price depends on where it is billed: about $38.90 from a physician practice, and about $75.86 from a hospital or other facility.

Work out the cost of a dose

This drug is priced per mg. Enter the amount given to see what insurers have agreed to pay for it.

mg
In a doctor's office or clinic
$38.90
At a hospital outpatient department
$75.86

The same drug, in the same amount, costs 95% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$38.90$36.31 to $39.81
FacilityA hospital or hospital-owned outpatient department$75.86$51.29 to $129

How much rates vary

Facilitymedian $76 · 10th to 90th $32 to $195Professionalmedian $39 · 10th to 90th $36 to $41
$20$50$100$200facility $76professional $39

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$51.29
Median
$56.23
Typical High
$74.13
Aetna
Setting
Professional
Modifier
None
Typical Low
$38.90
Median
$38.90
Typical High
$38.90
BCBS Arizona
Setting
Facility
Modifier
None
Typical Low
$30.90
Median
$95.50
Typical High
$208.93
BCBS Arizona
Setting
Professional
Modifier
None
Typical Low
$38.02
Median
$38.02
Typical High
$269.15
Cigna
Setting
Facility
Modifier
None
Typical Low
$50.12
Median
$70.79
Typical High
$75.86
Cigna
Setting
Professional
Modifier
None
Typical Low
$40.74
Median
$40.74
Typical High
$40.74
Medica
Setting
Facility
Modifier
None
Typical Low
$35.48
Median
$42.66
Typical High
$85.11
Medica
Setting
Professional
Modifier
None
Typical Low
$36.31
Median
$36.31
Typical High
$36.31
United
Setting
Professional
Modifier
None
Typical Low
$39.81
Median
$39.81
Typical High
$39.81
4 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$19.50
Median
$19.50
Typical High
$19.50
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$7.76
Median
$7.76
Typical High
$7.76
Aetna
Setting
Professional
Modifier
55 · Aftercare only
Typical Low
$5.75
Median
$5.75
Typical High
$5.75
Aetna
Setting
Professional
Modifier
56 · Pre-op care only
Typical Low
$3.89
Median
$3.89
Typical High
$3.89

Where Arizona sits

The same service costs 1.8 times more in Alaska than in Nebraska. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Arizona· 2nd of 51

$56.23

AK $64.57NE $36.31

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.