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Plasminogen Injection

Alaska rates for HCPCS J2998 · Ryplazim

Injection, plasminogen, human-tvmh, 1 mg

Rates data updated July 2026.

How much does Ryplazim (plasminogen) cost?

$64.57per mg

Typical negotiated rate. In Alaska, July 2026.

Insurers have agreed to pay about $64.57 for each mg of this drug. The price depends on where it is billed: about $64.57 from a physician practice, and about $69.18 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

Work out the cost of a dose

This drug is priced per mg. Enter the amount given to see what insurers have agreed to pay for it.

mg
In a doctor's office or clinic
$64.57
At a hospital outpatient department
$69.18

The same drug, in the same amount, costs 7% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$64.57$64.57 to $67.61
FacilityA hospital or hospital-owned outpatient department$69.18$54.95 to $95.50

How much rates vary

Facilitymedian $69 · 10th to 90th $55 to $224Professionalmedian $65 · 10th to 90th $41 to $68
$50$100$200facility $69professional $65

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$223.87
Median
$223.87
Typical High
$223.87
Aetna
Setting
Professional
Modifier
Global
Typical Low
$64.57
Median
$64.57
Typical High
$67.61
Cigna
Setting
Professional
Modifier
Global
Typical Low
$40.74
Median
$40.74
Typical High
$40.74
Moda Health
Setting
Facility
Modifier
Global
Typical Low
$64.57
Median
$64.57
Typical High
$93.33
Premera BCBS
Setting
Facility
Modifier
Global
Typical Low
$34.67
Median
$54.95
Typical High
$95.50
Providence
Setting
Facility
Modifier
Global
Typical Low
$64.57
Median
$64.57
Typical High
$93.33
Providence
Setting
Professional
Modifier
Global
Typical Low
$40.74
Median
$40.74
Typical High
$40.74
United
Setting
Professional
Modifier
Global
Typical Low
$39.81
Median
$39.81
Typical High
$81.28

Where Alaska sits

The same service costs 1.9 times more in Colorado than in North Carolina. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Alaska· 2nd of 51

$64.57

CO $66.07NC $33.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.