How much does Sylvant (siltuximab) cost?

$174per 10 mg

Typical negotiated rate. In Vermont, July 2026.

Insurers have agreed to pay about $174 for each 10 mg of this drug. The price depends on where it is billed: about $174 from a physician practice, and about $186 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

Work out the cost of a dose

This drug is priced per 10 mg. Enter the amount given to see what insurers have agreed to pay for it.

Amount givenmg

In a doctor's office or clinic: $174
At a hospital outpatient department: $186

The same drug, in the same amount, costs 7% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed by	Who charges it	Typical	Range
Physician practiceA doctor's office, clinic or independent provider	A doctor's office, clinic or independent provider	$174	$174 to $178
FacilityA hospital or hospital-owned outpatient department	A hospital or hospital-owned outpatient department	$186	$186 to $186

How much rates vary

Facilitymedian $186 · 10th to 90th $186 to $195Professionalmedian $174 · 10th to 90th $170 to $302

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier	Facility/Professional	Modifier	Typical Low	Median	Typical High
Aetna Setting Professional Modifier Global Typical Low $173.78 Median $173.78 Typical High $302.00	Professional	Global	$173.78	$173.78	$302.00
BCBS Setting Facility Modifier Global Typical Low $186.21 Median $186.21 Typical High $186.21	Facility	Global	$186.21	$186.21	$186.21
Cigna Setting Facility Modifier Global Typical Low $186.21 Median $186.21 Typical High $194.98	Facility	Global	$186.21	$186.21	$194.98
Cigna Setting Professional Modifier Global Typical Low $173.78 Median $173.78 Typical High $186.21	Professional	Global	$173.78	$173.78	$186.21
United Setting Facility Modifier Global Typical Low $190.55 Median $190.55 Typical High $190.55	Facility	Global	$190.55	$190.55	$190.55
United Setting Professional Modifier Global Typical Low $77.62 Median $169.82 Typical High $181.97	Professional	Global	$77.62	$169.82	$181.97

Where Vermont sits

The same service costs 2.9 times more in Delaware than in Oklahoma. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Vermont· 45th of 51

$174

DE $372OK $129

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.