How much does Methylnaltrexone Injection cost?

$1.51per 0.1 mg

Typical negotiated rate. In Nebraska, July 2026.

Insurers have agreed to pay about $1.51 for each 0.1 mg of this drug. The price depends on where it is billed: about $1.51 from a physician practice, and about $3.02 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

Work out the cost of a dose

This drug is priced per 0.1 mg. Enter the amount given to see what insurers have agreed to pay for it.

Amount givenmg

In a doctor's office or clinic: $1.51
At a hospital outpatient department: $3.02

The same drug, in the same amount, costs 100% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed by	Who charges it	Typical	Range
Physician practiceA doctor's office, clinic or independent provider	A doctor's office, clinic or independent provider	$1.51	$1.51 to $1.51
FacilityA hospital or hospital-owned outpatient department	A hospital or hospital-owned outpatient department	$3.02	$2.57 to $4.27

How much rates vary

Facilitymedian $3 · 10th to 90th $2 to $4Professionalmedian $2 · 10th to 90th $1 to $2

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier	Facility/Professional	Modifier	Typical Low	Median	Typical High
Aetna Setting Facility Modifier Global Typical Low $1.51 Median $3.02 Typical High $4.27	Facility	Global	$1.51	$3.02	$4.27
Aetna Setting Professional Modifier Global Typical Low $1.51 Median $1.51 Typical High $1.51	Professional	Global	$1.51	$1.51	$1.51
Cigna Setting Professional Modifier Global Typical Low $0.38 Median $0.47 Typical High $1.58	Professional	Global	$0.38	$0.47	$1.58
Medica Setting Facility Modifier Global Typical Low $1.35 Median $85.11 Typical High $281.84	Facility	Global	$1.35	$85.11	$281.84
Medica Setting Professional Modifier Global Typical Low $1.41 Median $1.41 Typical High $1.91	Professional	Global	$1.41	$1.41	$1.91
United Setting Facility Modifier Global Typical Low $2.09 Median $3.47 Typical High $5.62	Facility	Global	$2.09	$3.47	$5.62
United Setting Professional Modifier Global Typical Low $1.48 Median $1.55 Typical High $2.09	Professional	Global	$1.48	$1.55	$2.09

Where Nebraska sits

The same service costs 3.0 times more in Colorado than in Kentucky. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Nebraska· 47th of 51

$1.51

CO $2.69KY $0.91

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.