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Galsulfase Injection

Massachusetts rates for HCPCS J1458 · Naglazyme

Injection, galsulfase, 1 mg

Rates data updated October 2026.

How much does Naglazyme (galsulfase) cost?

$525per mg

Typical negotiated rate. In Massachusetts, October 2026.

Insurers have agreed to pay about $525 for each mg of this drug. The price depends on where it is billed: about $525 from a physician practice, and about $676 from a hospital or other facility.

Work out the cost of a dose

This drug is priced per mg. Enter the amount given to see what insurers have agreed to pay for it.

mg
In a doctor's office or clinic
$525
At a hospital outpatient department
$676

The same drug, in the same amount, costs 29% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 9 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$525$513 to $525
FacilityA hospital or hospital-owned outpatient department$676$525 to $1,000

How much rates vary

Facilitymedian $676 · 10th to 90th $513 to $1,445Professionalmedian $525 · 10th to 90th $513 to $794
$100$200$500$1K$2Kfacility $676professional $525

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$524.81
Median
$524.81
Typical High
$912.01
Aetna
Setting
Professional
Modifier
None
Typical Low
$524.81
Median
$524.81
Typical High
$549.54
AllWays Health Partners
Setting
Facility
Modifier
None
Typical Low
$407.38
Median
$575.44
Typical High
$1,698.24
AllWays Health Partners
Setting
Professional
Modifier
None
Typical Low
$512.86
Median
$524.81
Typical High
$776.25
BCBS Massachusetts
Setting
Facility
Modifier
None
Typical Low
$524.81
Median
$602.56
Typical High
$1,096.48
Cigna
Setting
Facility
Modifier
None
Typical Low
$676.08
Median
$1,096.48
Typical High
$2,290.87
Cigna
Setting
Professional
Modifier
None
Typical Low
$524.81
Median
$524.81
Typical High
$602.56
Fallon Health
Setting
Facility
Modifier
None
Typical Low
$512.86
Median
$676.08
Typical High
$1,023.29
Harvard Pilgrim
Setting
Professional
Modifier
None
Typical Low
$512.86
Median
$524.81
Typical High
$870.96
Mass General Brigham
Setting
Facility
Modifier
None
Typical Low
$407.38
Median
$575.44
Typical High
$1,698.24
Mass General Brigham
Setting
Professional
Modifier
None
Typical Low
$512.86
Median
$524.81
Typical High
$776.25
United
Setting
Facility
Modifier
None
Typical Low
$524.81
Median
$524.81
Typical High
$524.81
United
Setting
Professional
Modifier
None
Typical Low
$512.86
Median
$512.86
Typical High
$870.96
Well Sense
Setting
Facility
Modifier
None
Typical Low
$562.34
Median
$776.25
Typical High
$1,230.27
Well Sense
Setting
Professional
Modifier
None
Typical Low
$524.81
Median
$524.81
Typical High
$630.96

Where Massachusetts sits

The same service costs 1.6 times more in Arizona than in Iowa. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Massachusetts· 25th of 51

$525

AZ $832IA $513

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.