How much does Depo-Estradiol (estradiol cypionate) cost?

$53.70per dose

One 5 mg dose, at the doctor's office rate. In Vermont, October 2026.

Negotiated ratewhat insurers pay per 5 mg of the drug: $53.70 / 5 mg
Average doseacross Medicare claims, discarded units included: × 5 mg
One dosedrug only; giving it and the visit are billed separately: $53.70

Work out the cost of a dose

This drug is priced per 5 mg. Enter the amount given to see what insurers have agreed to pay for it. Prefilled with the average administration in Medicare claims, discarded units included.

Amount givenmg

In a doctor's office or clinic: $53.70

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

Few insurers publish rates for this combination, so treat this figure as a rough guide.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $59 · 10th to 90th $59 to $60Professionalmedian $54 · 10th to 90th $51 to $59

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier	Facility/Professional	Modifier	Typical Low	Median	Typical High
Aetna Setting Professional Modifier None Typical Low $53.70 Median $53.70 Typical High $60.26	Professional	None	$53.70	$53.70	$60.26
BCBS Vermont Setting Facility Modifier None Typical Low $58.88 Median $58.88 Typical High $58.88	Facility	None	$58.88	$58.88	$58.88
Cigna Setting Facility Modifier None Typical Low $58.88 Median $60.26 Typical High $60.26	Facility	None	$58.88	$60.26	$60.26
Cigna Setting Professional Modifier None Typical Low $53.70 Median $53.70 Typical High $58.88	Professional	None	$53.70	$53.70	$58.88
United Setting Professional Modifier None Typical Low $48.98 Median $51.29 Typical High $56.23	Professional	None	$48.98	$51.29	$56.23

Where Vermont sits

The same service costs 3.0 times more in Arizona than in Oklahoma. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Vermont· 41st of 51

$53.70

AZ $81.28OK $27.54

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.