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Depo-Estradiol Cypionate Injection

Massachusetts rates for HCPCS J1000

Injection, depo-estradiol cypionate, up to 5 mg

Rates data updated July 2026.

How much does Depo-Estradiol (estradiol cypionate) cost?

$51.29per dose

One 5 mg dose, at the doctor's office rate. In Massachusetts, July 2026.

Negotiated ratewhat insurers pay per 5 mg of the drug
$51.29 / 5 mg
Average doseacross Medicare claims, discarded units included
× 5 mg
One dosedrug only; giving it and the visit are billed separately
$51.29

Work out the cost of a dose

This drug is priced per 5 mg. Enter the amount given to see what insurers have agreed to pay for it. Prefilled with the average administration in Medicare claims, discarded units included.

mg
In a doctor's office or clinic
$51.29
At a hospital outpatient department
$58.88

The same drug, in the same amount, costs 15% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where the price changes

Given atPer 5 mgPer 5 mg dose
Doctor's office or clinic$51.29$51.29
Hospital outpatient department$58.88$58.88

How much rates vary

Facilitymedian $59 · 10th to 90th $51 to $141Professionalmedian $51 · 10th to 90th $51 to $83
$10.0$100.0$1.0K$10.0Kfacility $59professional $51

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$51.29
Median
$72.44
Typical High
$107.15
Aetna
Setting
Professional
Modifier
Global
Typical Low
$17.78
Median
$51.29
Typical High
$53.70
AllWays Health Partners
Setting
Facility
Modifier
Global
Typical Low
$2.75
Median
$17.78
Typical High
$173.78
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$51.29
Median
$53.70
Typical High
$64.57
BCBS
Setting
Facility
Modifier
Global
Typical Low
$51.29
Median
$51.29
Typical High
$102.33
Cigna
Setting
Facility
Modifier
Global
Typical Low
$67.61
Median
$109.65
Typical High
$223.87
Cigna
Setting
Professional
Modifier
Global
Typical Low
$47.86
Median
$51.29
Typical High
$51.29
Fallon Health
Setting
Facility
Modifier
Global
Typical Low
$51.29
Median
$75.86
Typical High
$6,918.31
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$51.29
Median
$51.29
Typical High
$87.10
Mass General Brigham
Setting
Facility
Modifier
Global
Typical Low
$2.75
Median
$17.78
Typical High
$173.78
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$51.29
Median
$53.70
Typical High
$64.57
United
Setting
Facility
Modifier
Global
Typical Low
$51.29
Median
$112.20
Typical High
$112.20
United
Setting
Professional
Modifier
Global
Typical Low
$51.29
Median
$51.29
Typical High
$63.10

Where Massachusetts sits

The same service costs 3.0 times more in Delaware than in Oklahoma. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Massachusetts $51.29 · 43rd of 51
DE $89.13OK $29.51

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.