How much does Depo-Estradiol (estradiol cypionate) cost?

$46.77per dose

One 5 mg dose, at the doctor's office rate. In Hawaii, October 2026.

Negotiated ratewhat insurers pay per 5 mg of the drug: $46.77 / 5 mg
Average doseacross Medicare claims, discarded units included: × 5 mg
One dosedrug only; giving it and the visit are billed separately: $46.77

Work out the cost of a dose

This drug is priced per 5 mg. Enter the amount given to see what insurers have agreed to pay for it. Prefilled with the average administration in Medicare claims, discarded units included.

Amount givenmg

In a doctor's office or clinic: $46.77

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $47 · 10th to 90th $10 to $63

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier	Facility/Professional	Modifier	Typical Low	Median	Typical High
Cigna Setting Professional Modifier None Typical Low $46.77 Median $46.77 Typical High $53.70	Professional	None	$46.77	$46.77	$53.70
HMSA Setting Professional Modifier None Typical Low $50.12 Median $50.12 Typical High $50.12	Professional	None	$50.12	$50.12	$50.12
Kaiser Permanente Setting Professional Modifier None Typical Low $57.54 Median $61.66 Typical High $100.00	Professional	None	$57.54	$61.66	$100.00
United Setting Professional Modifier None Typical Low $46.77 Median $46.77 Typical High $77.62	Professional	None	$46.77	$46.77	$77.62
University Health Alliance Setting Professional Modifier None Typical Low $10.23 Median $23.99 Typical High $46.77	Professional	None	$10.23	$23.99	$46.77

Where Hawaii sits

The same service costs 3.0 times more in Arizona than in Oklahoma. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Hawaii· 50th of 51

$46.77

AZ $81.28OK $27.54

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.