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Crizanlizumab-tmca Injection

Massachusetts rates for HCPCS J0791 · Adakveo

Injection, crizanlizumab-tmca, 5 mg

Rates data updated October 2026.

How much does Adakveo (crizanlizumab) cost?

$129per 5 mg

Typical negotiated rate. In Massachusetts, October 2026.

Insurers have agreed to pay about $129 for each 5 mg of this drug. The price depends on where it is billed: about $129 from a physician practice, and about $170 from a hospital or other facility.

Work out the cost of a dose

This drug is priced per 5 mg. Enter the amount given to see what insurers have agreed to pay for it.

mg
In a doctor's office or clinic
$129
At a hospital outpatient department
$170

The same drug, in the same amount, costs 32% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 9 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$129$129 to $135
FacilityA hospital or hospital-owned outpatient department$170$129 to $234

How much rates vary

Facilitymedian $170 · 10th to 90th $126 to $355Professionalmedian $129 · 10th to 90th $129 to $195
$100$200$500facility $170professional $129

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$128.82
Median
$128.82
Typical High
$128.82
Aetna
Setting
Professional
Modifier
None
Typical Low
$128.82
Median
$128.82
Typical High
$147.91
AllWays Health Partners
Setting
Facility
Modifier
None
Typical Low
$125.89
Median
$144.54
Typical High
$426.58
AllWays Health Partners
Setting
Professional
Modifier
None
Typical Low
$125.89
Median
$128.82
Typical High
$194.98
BCBS Massachusetts
Setting
Facility
Modifier
None
Typical Low
$128.82
Median
$147.91
Typical High
$269.15
Cigna
Setting
Facility
Modifier
None
Typical Low
$154.88
Median
$234.42
Typical High
$562.34
Cigna
Setting
Professional
Modifier
None
Typical Low
$128.82
Median
$128.82
Typical High
$158.49
Fallon Health
Setting
Facility
Modifier
None
Typical Low
$128.82
Median
$169.82
Typical High
$194.98
Harvard Pilgrim
Setting
Professional
Modifier
None
Typical Low
$128.82
Median
$128.82
Typical High
$218.78
Mass General Brigham
Setting
Facility
Modifier
None
Typical Low
$125.89
Median
$144.54
Typical High
$426.58
Mass General Brigham
Setting
Professional
Modifier
None
Typical Low
$125.89
Median
$128.82
Typical High
$194.98
United
Setting
Facility
Modifier
None
Typical Low
$128.82
Median
$128.82
Typical High
$128.82
United
Setting
Professional
Modifier
None
Typical Low
$125.89
Median
$128.82
Typical High
$218.78
Well Sense
Setting
Facility
Modifier
None
Typical Low
$128.82
Median
$177.83
Typical High
$269.15
Well Sense
Setting
Professional
Modifier
None
Typical Low
$128.82
Median
$128.82
Typical High
$154.88
4 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$64.57
Median
$64.57
Typical High
$64.57
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$25.70
Median
$25.70
Typical High
$25.70
Aetna
Setting
Professional
Modifier
55 · Aftercare only
Typical Low
$19.50
Median
$19.50
Typical High
$19.50
Aetna
Setting
Professional
Modifier
56 · Pre-op care only
Typical Low
$12.88
Median
$12.88
Typical High
$12.88

Where Massachusetts sits

The same service costs 1.6 times more in Texas than in North Carolina. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Massachusetts· 37th of 51

$129

TX $204NC $129

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.