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C1 Esterase Inhibitor (Cinryze) Injection

South Dakota rates for HCPCS J0598

Injection, C1 esterase inhibitor (human), Cinryze, 10 units

Rates data updated October 2026.

How much does Cinryze (human c1-esterase inhibitor) cost?

$67.61per 10 units

Typical negotiated rate. In South Dakota, October 2026.

Insurers have agreed to pay about $67.61 for each 10 units of this drug. The price depends on where it is billed: about $67.61 from a physician practice, and about $66.07 from a hospital or other facility.

Work out the cost of a dose

This drug is priced per 10 units. Enter the amount given to see what insurers have agreed to pay for it.

units
In a doctor's office or clinic
$67.61
At a hospital outpatient department
$66.07

The same drug, in the same amount, costs 2% less at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$67.61$66.07 to $72.44
FacilityA hospital or hospital-owned outpatient department$66.07$66.07 to $91.20

How much rates vary

Facilitymedian $66 · 10th to 90th $66 to $112Professionalmedian $68 · 10th to 90th $66 to $85
$100facility $66professional $68

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$66.07
Median
$66.07
Typical High
$72.44
Aetna
Setting
Professional
Modifier
None
Typical Low
$66.07
Median
$66.07
Typical High
$66.07
Cigna
Setting
Facility
Modifier
None
Typical Low
$67.61
Median
$67.61
Typical High
$67.61
Cigna
Setting
Professional
Modifier
None
Typical Low
$67.61
Median
$67.61
Typical High
$85.11
Medica
Setting
Facility
Modifier
None
Typical Low
$70.79
Median
$112.20
Typical High
$112.20
Medica
Setting
Professional
Modifier
None
Typical Low
$56.23
Median
$66.07
Typical High
$72.44
Midlands
Setting
Professional
Modifier
None
Typical Low
$79.43
Median
$79.43
Typical High
$79.43
Sanford Health Plan
Setting
Professional
Modifier
None
Typical Low
$67.61
Median
$72.44
Typical High
$72.44
United
Setting
Professional
Modifier
None
Typical Low
$66.07
Median
$66.07
Typical High
$72.44
Wellmark
Setting
Facility
Modifier
None
Typical Low
$66.07
Median
$66.07
Typical High
$66.07
Wellmark
Setting
Professional
Modifier
None
Typical Low
$66.07
Median
$66.07
Typical High
$66.07

Where South Dakota sits

The same service costs 1.6 times more in Arizona than in Florida. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Dakota· 21st of 51

$67.61

AZ $107FL $66.07

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.