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C1 Esterase Inhibitor (Cinryze) Injection

Pennsylvania rates for HCPCS J0598

Injection, C1 esterase inhibitor (human), Cinryze, 10 units

Rates data updated October 2026.

How much does Cinryze (human c1-esterase inhibitor) cost?

$67.61per 10 units

Typical negotiated rate. In Pennsylvania, October 2026.

Insurers have agreed to pay about $67.61 for each 10 units of this drug. The price depends on where it is billed: about $66.07 from a physician practice, and about $77.62 from a hospital or other facility.

Work out the cost of a dose

This drug is priced per 10 units. Enter the amount given to see what insurers have agreed to pay for it.

units
In a doctor's office or clinic
$66.07
At a hospital outpatient department
$77.62

The same drug, in the same amount, costs 17% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$66.07$66.07 to $67.61
FacilityA hospital or hospital-owned outpatient department$77.62$66.07 to $95.50

How much rates vary

Facilitymedian $78 · 10th to 90th $66 to $245Professionalmedian $66 · 10th to 90th $66 to $74
$100$200facility $78professional $66

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$66.07
Median
$95.50
Typical High
$173.78
Aetna
Setting
Professional
Modifier
None
Typical Low
$66.07
Median
$67.61
Typical High
$67.61
Capital Blue Cross
Setting
Facility
Modifier
None
Typical Low
$63.10
Median
$72.44
Typical High
$85.11
Capital Blue Cross
Setting
Professional
Modifier
None
Typical Low
$69.18
Median
$69.18
Typical High
$72.44
Cigna
Setting
Facility
Modifier
None
Typical Low
$66.07
Median
$112.20
Typical High
$257.04
Cigna
Setting
Professional
Modifier
None
Typical Low
$66.07
Median
$66.07
Typical High
$66.07
Geisinger
Setting
Facility
Modifier
None
Typical Low
$66.07
Median
$66.07
Typical High
$66.07
Geisinger
Setting
Professional
Modifier
None
Typical Low
$100.00
Median
$100.00
Typical High
$120.23
Martin's Point
Setting
Facility
Modifier
None
Typical Low
$66.07
Median
$100.00
Typical High
$173.78
Martin's Point
Setting
Professional
Modifier
None
Typical Low
$66.07
Median
$67.61
Typical High
$67.61
UPMC Health Plan
Setting
Facility
Modifier
None
Typical Low
$60.26
Median
$77.62
Typical High
$81.28
UPMC Health Plan
Setting
Professional
Modifier
None
Typical Low
$60.26
Median
$60.26
Typical High
$70.79
United
Setting
Facility
Modifier
None
Typical Low
$66.07
Median
$66.07
Typical High
$66.07
United
Setting
Professional
Modifier
None
Typical Low
$66.07
Median
$66.07
Typical High
$91.20
1 more rate with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Highmark BCBS
Setting
Facility
Modifier
JZ · No drug discarded
Typical Low
$239.88
Median
$239.88
Typical High
$239.88

Where Pennsylvania sits

The same service costs 1.6 times more in Arizona than in Florida. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Pennsylvania· 23rd of 51

$67.61

AZ $107FL $66.07

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.