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C1 Esterase Inhibitor (Cinryze) Injection

North Carolina rates for HCPCS J0598

Injection, C1 esterase inhibitor (human), Cinryze, 10 units

Rates data updated July 2026.

How much does Cinryze (human c1-esterase inhibitor) cost?

$67.61per 10 units

Typical negotiated rate. In North Carolina, July 2026.

Insurers have agreed to pay about $67.61 for each 10 units of this drug. The price depends on where it is billed: about $66.07 from a physician practice, and about $74.13 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

Work out the cost of a dose

This drug is priced per 10 units. Enter the amount given to see what insurers have agreed to pay for it.

units
In a doctor's office or clinic
$66.07
At a hospital outpatient department
$74.13

The same drug, in the same amount, costs 12% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$66.07$60.26 to $79.43
FacilityA hospital or hospital-owned outpatient department$74.13$64.57 to $115

How much rates vary

Facilitymedian $74 · 10th to 90th $49 to $135Professionalmedian $66 · 10th to 90th $59 to $115
$50$100facility $74professional $66

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$48.98
Median
$67.61
Typical High
$114.82
Aetna
Setting
Professional
Modifier
Global
Typical Low
$58.88
Median
$66.07
Typical High
$114.82
BCBS
Setting
Facility
Modifier
Global
Typical Low
$77.62
Median
$117.49
Typical High
$134.90
BCBS
Setting
Professional
Modifier
Global
Typical Low
$57.54
Median
$57.54
Typical High
$67.61
Cigna
Setting
Facility
Modifier
Global
Typical Low
$74.13
Median
$97.72
Typical High
$154.88
Cigna
Setting
Professional
Modifier
Global
Typical Low
$66.07
Median
$66.07
Typical High
$77.62
Medcost
Setting
Facility
Modifier
Global
Typical Low
$60.26
Median
$66.07
Typical High
$77.62
United
Setting
Facility
Modifier
Global
Typical Low
$66.07
Median
$107.15
Typical High
$120.23
United
Setting
Professional
Modifier
Global
Typical Low
$66.07
Median
$66.07
Typical High
$85.11
Wellcare
Setting
Facility
Modifier
Global
Typical Low
$331.13
Median
$331.13
Typical High
$331.13

Where North Carolina sits

The same service costs 2.3 times more in Delaware than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

North Carolina· 28th of 51

$67.61

DE $155AL $66.07

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.