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C1 Esterase Inhibitor (Cinryze) Injection

North Carolina rates for HCPCS J0598

Injection, C1 esterase inhibitor (human), Cinryze, 10 units

Rates data updated October 2026.

How much does Cinryze (human c1-esterase inhibitor) cost?

$66.07per 10 units

Typical negotiated rate. In North Carolina, October 2026.

Insurers have agreed to pay about $66.07 for each 10 units of this drug. The price depends on where it is billed: about $66.07 from a physician practice, and about $87.10 from a hospital or other facility.

Work out the cost of a dose

This drug is priced per 10 units. Enter the amount given to see what insurers have agreed to pay for it.

units
In a doctor's office or clinic
$66.07
At a hospital outpatient department
$87.10

The same drug, in the same amount, costs 32% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$66.07$60.26 to $66.07
FacilityA hospital or hospital-owned outpatient department$87.10$74.13 to $107

How much rates vary

Facilitymedian $87 · 10th to 90th $60 to $135Professionalmedian $66 · 10th to 90th $60 to $78
$50$100facility $87professional $66

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$60.26
Median
$60.26
Typical High
$83.18
Aetna
Setting
Professional
Modifier
None
Typical Low
$60.26
Median
$60.26
Typical High
$69.18
BCBS North Carolina
Setting
Facility
Modifier
None
Typical Low
$67.61
Median
$93.33
Typical High
$134.90
BCBS North Carolina
Setting
Professional
Modifier
None
Typical Low
$57.54
Median
$57.54
Typical High
$67.61
Cigna
Setting
Facility
Modifier
None
Typical Low
$75.86
Median
$100.00
Typical High
$151.36
Cigna
Setting
Professional
Modifier
None
Typical Low
$66.07
Median
$66.07
Typical High
$77.62
Medcost
Setting
Facility
Modifier
None
Typical Low
$60.26
Median
$60.26
Typical High
$79.43
Medcost
Setting
Professional
Modifier
None
Typical Low
$42.66
Median
$42.66
Typical High
$42.66
United
Setting
Professional
Modifier
None
Typical Low
$66.07
Median
$66.07
Typical High
$85.11

Where North Carolina sits

The same service costs 1.6 times more in Arizona than in Florida. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

North Carolina· 33rd of 51

$66.07

AZ $107FL $66.07

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.