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C1 Esterase Inhibitor (Cinryze) Injection

Minnesota rates for HCPCS J0598

Injection, C1 esterase inhibitor (human), Cinryze, 10 units

Rates data updated July 2026.

How much does Cinryze (human c1-esterase inhibitor) cost?

$66.07per 10 units

Typical negotiated rate. In Minnesota, July 2026.

Insurers have agreed to pay about $66.07 for each 10 units of this drug. The price depends on where it is billed: about $66.07 from a physician practice, and about $67.61 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

Work out the cost of a dose

This drug is priced per 10 units. Enter the amount given to see what insurers have agreed to pay for it.

units
In a doctor's office or clinic
$66.07
At a hospital outpatient department
$67.61

The same drug, in the same amount, costs 2% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$66.07$64.57 to $66.07
FacilityA hospital or hospital-owned outpatient department$67.61$67.61 to $87.10

How much rates vary

Facilitymedian $68 · 10th to 90th $65 to $132Professionalmedian $66 · 10th to 90th $52 to $69
$100$200facility $68professional $66

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$66.07
Median
$66.07
Typical High
$131.83
Aetna
Setting
Professional
Modifier
Global
Typical Low
$66.07
Median
$66.07
Typical High
$83.18
BCBS
Setting
Facility
Modifier
Global
Typical Low
$64.57
Median
$125.89
Typical High
$131.83
BCBS
Setting
Professional
Modifier
Global
Typical Low
$52.48
Median
$66.07
Typical High
$66.07
Cigna
Setting
Facility
Modifier
Global
Typical Low
$67.61
Median
$70.79
Typical High
$190.55
Cigna
Setting
Professional
Modifier
Global
Typical Low
$67.61
Median
$77.62
Typical High
$85.11
Health Partners
Setting
Facility
Modifier
Global
Typical Low
$67.61
Median
$67.61
Typical High
$67.61
Health Partners
Setting
Professional
Modifier
Global
Typical Low
$66.07
Median
$66.07
Typical High
$70.79
Medica
Setting
Facility
Modifier
Global
Typical Low
$52.48
Median
$66.07
Typical High
$112.20
Medica
Setting
Professional
Modifier
Global
Typical Low
$66.07
Median
$66.07
Typical High
$89.13
United
Setting
Facility
Modifier
Global
Typical Low
$66.07
Median
$66.07
Typical High
$66.07
United
Setting
Professional
Modifier
Global
Typical Low
$66.07
Median
$66.07
Typical High
$123.03

Where Minnesota sits

The same service costs 2.3 times more in Delaware than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Minnesota· 39th of 51

$66.07

DE $155AL $66.07

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.