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C1 Esterase Inhibitor (Cinryze) Injection

Iowa rates for HCPCS J0598

Injection, C1 esterase inhibitor (human), Cinryze, 10 units

Rates data updated July 2026.

How much does Cinryze (human c1-esterase inhibitor) cost?

$72.44per 10 units

Typical negotiated rate. In Iowa, July 2026.

Insurers have agreed to pay about $72.44 for each 10 units of this drug. The price depends on where it is billed: about $72.44 from a physician practice, and about $66.07 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

Work out the cost of a dose

This drug is priced per 10 units. Enter the amount given to see what insurers have agreed to pay for it.

units
In a doctor's office or clinic
$72.44
At a hospital outpatient department
$66.07

The same drug, in the same amount, costs 9% less at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$72.44$66.07 to $83.18
FacilityA hospital or hospital-owned outpatient department$66.07$66.07 to $72.44

How much rates vary

Facilitymedian $66 · 10th to 90th $66 to $100Professionalmedian $72 · 10th to 90th $66 to $155
$50$100$200facility $66professional $72

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$66.07
Median
$72.44
Typical High
$131.83
Aetna
Setting
Professional
Modifier
Global
Typical Low
$66.07
Median
$72.44
Typical High
$154.88
Cigna
Setting
Facility
Modifier
Global
Typical Low
$67.61
Median
$67.61
Typical High
$67.61
Cigna
Setting
Professional
Modifier
Global
Typical Low
$66.07
Median
$72.44
Typical High
$83.18
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$46.77
Median
$66.07
Typical High
$2,570.40
Medica
Setting
Facility
Modifier
Global
Typical Low
$60.26
Median
$70.79
Typical High
$112.20
Medica
Setting
Professional
Modifier
Global
Typical Low
$56.23
Median
$66.07
Typical High
$95.50
Midlands
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$83.18
Typical High
$83.18
United
Setting
Facility
Modifier
Global
Typical Low
$60.26
Median
$66.07
Typical High
$66.07
United
Setting
Professional
Modifier
Global
Typical Low
$66.07
Median
$66.07
Typical High
$69.18
Wellmark
Setting
Facility
Modifier
Global
Typical Low
$66.07
Median
$66.07
Typical High
$66.07

Where Iowa sits

The same service costs 2.3 times more in Delaware than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Iowa· 17th of 51

$72.44

DE $155AL $66.07

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.