How much does Cinryze (human c1-esterase inhibitor) cost?

$5,623per 10 units

Typical negotiated rate. In Alabama, October 2026.

Insurers have agreed to pay about $5,623 for each 10 units of this drug. The price depends on where it is billed: about $66.07 from a physician practice, and about $5,623 from a hospital or other facility.

Work out the cost of a dose

This drug is priced per 10 units. Enter the amount given to see what insurers have agreed to pay for it.

Amount givenunits

In a doctor's office or clinic: $66.07
At a hospital outpatient department: $5,623

The same drug, in the same amount, costs 8411% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Prices by location type

Billed by	Who charges it	Typical	Range
Physician practiceA doctor's office, clinic or independent provider	A doctor's office, clinic or independent provider	$66.07	$66.07 to $66.07
FacilityA hospital or hospital-owned outpatient department	A hospital or hospital-owned outpatient department	$5,623	$5,623 to $5,754

How much rates vary

Facilitymedian $5,623 · 10th to 90th $87 to $5,754Professionalmedian $66 · 10th to 90th $66 to $66

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier	Facility/Professional	Modifier	Typical Low	Median	Typical High
Aetna Setting Professional Modifier None Typical Low $66.07 Median $66.07 Typical High $66.07	Professional	None	$66.07	$66.07	$66.07
BCBS Setting Facility Modifier None Typical Low $5,623.41 Median $5,754.40 Typical High $5,754.40	Facility	None	$5,623.41	$5,754.40	$5,754.40
BCBS Setting Professional Modifier 12 Typical Low $66.07 Median $66.07 Typical High $66.07	Professional	12	$66.07	$66.07	$66.07
Cigna Setting Facility Modifier None Typical Low $66.07 Median $69.18 Typical High $87.10	Facility	None	$66.07	$69.18	$87.10
Cigna Setting Professional Modifier None Typical Low $66.07 Median $66.07 Typical High $107.15	Professional	None	$66.07	$66.07	$107.15
United Setting Facility Modifier None Typical Low $66.07 Median $66.07 Typical High $66.07	Facility	None	$66.07	$66.07	$66.07
United Setting Professional Modifier None Typical Low $66.07 Median $66.07 Typical High $66.07	Professional	None	$66.07	$66.07	$66.07

Where Alabama sits

The same service costs 85.1 times more in Alabama than in Maryland. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Alabama· 1st of 51

$5,623

AL $5,623MD $66.07

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.