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Burosumab-twza Injection

North Carolina rates for HCPCS J0584 · Crysvita

Injection, burosumab-twza, 1 mg

Rates data updated October 2026.

How much does Crysvita (burosumab) cost?

$513per mg

Typical negotiated rate. In North Carolina, October 2026.

Insurers have agreed to pay about $513 for each mg of this drug. The price depends on where it is billed: about $501 from a physician practice, and about $776 from a hospital or other facility.

Work out the cost of a dose

This drug is priced per mg. Enter the amount given to see what insurers have agreed to pay for it.

mg
In a doctor's office or clinic
$501
At a hospital outpatient department
$776

The same drug, in the same amount, costs 55% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$501$417 to $513
FacilityA hospital or hospital-owned outpatient department$776$575 to $977

How much rates vary

Facilitymedian $776 · 10th to 90th $417 to $1,023Professionalmedian $501 · 10th to 90th $417 to $603
$500$1Kfacility $776professional $501

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$416.87
Median
$416.87
Typical High
$630.96
Aetna
Setting
Professional
Modifier
None
Typical Low
$416.87
Median
$416.87
Typical High
$524.81
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$208.93
Median
$208.93
Typical High
$263.03
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$83.18
Median
$83.18
Typical High
$104.71
Aetna
Setting
Professional
Modifier
55 · Aftercare only
Typical Low
$61.66
Median
$61.66
Typical High
$79.43
Aetna
Setting
Professional
Modifier
56 · Pre-op care only
Typical Low
$41.69
Median
$41.69
Typical High
$52.48
BCBS North Carolina
Setting
Facility
Modifier
None
Typical Low
$616.60
Median
$812.83
Typical High
$1,023.29
BCBS North Carolina
Setting
Professional
Modifier
None
Typical Low
$524.81
Median
$524.81
Typical High
$524.81
Cigna
Setting
Facility
Modifier
None
Typical Low
$575.44
Median
$776.25
Typical High
$1,148.15
Cigna
Setting
Professional
Modifier
None
Typical Low
$512.86
Median
$512.86
Typical High
$562.34
Medcost
Setting
Facility
Modifier
None
Typical Low
$416.87
Median
$416.87
Typical High
$616.60
Medcost
Setting
Professional
Modifier
None
Typical Low
$389.05
Median
$389.05
Typical High
$389.05
United
Setting
Professional
Modifier
None
Typical Low
$501.19
Median
$501.19
Typical High
$645.65

Where North Carolina sits

The same service costs 1.6 times more in Arizona than in Nebraska. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

North Carolina· 40th of 51

$513

AZ $813NE $501

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.