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Burosumab-twza Injection

Missouri rates for HCPCS J0584 · Crysvita

Injection, burosumab-twza, 1 mg

Rates data updated October 2026.

How much does Crysvita (burosumab) cost?

$513per mg

Typical negotiated rate. In Missouri, October 2026.

Insurers have agreed to pay about $513 for each mg of this drug. The price depends on where it is billed: about $513 from a physician practice, and about $676 from a hospital or other facility.

Work out the cost of a dose

This drug is priced per mg. Enter the amount given to see what insurers have agreed to pay for it.

mg
In a doctor's office or clinic
$513
At a hospital outpatient department
$676

The same drug, in the same amount, costs 32% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$513$501 to $575
FacilityA hospital or hospital-owned outpatient department$676$537 to $955

How much rates vary

Facilitymedian $676 · 10th to 90th $501 to $1,738Professionalmedian $513 · 10th to 90th $479 to $589
$200$500$1K$2Kfacility $676professional $513

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$501.19
Median
$588.84
Typical High
$812.83
Aetna
Setting
Professional
Modifier
None
Typical Low
$512.86
Median
$512.86
Typical High
$616.60
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$524.81
Median
$691.83
Typical High
$1,737.80
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$501.19
Median
$549.54
Typical High
$588.84
Cigna
Setting
Facility
Modifier
None
Typical Low
$588.84
Median
$891.25
Typical High
$1,202.26
Cigna
Setting
Professional
Modifier
None
Typical Low
$512.86
Median
$512.86
Typical High
$512.86
Medica
Setting
Facility
Modifier
None
Typical Low
$446.68
Median
$537.03
Typical High
$2,344.23
Medica
Setting
Professional
Modifier
None
Typical Low
$436.52
Median
$478.63
Typical High
$549.54
United
Setting
Facility
Modifier
None
Typical Low
$512.86
Median
$512.86
Typical High
$512.86
United
Setting
Professional
Modifier
None
Typical Low
$467.74
Median
$501.19
Typical High
$575.44
4 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$257.04
Median
$257.04
Typical High
$309.03
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$102.33
Median
$102.33
Typical High
$123.03
Aetna
Setting
Professional
Modifier
55 · Aftercare only
Typical Low
$77.62
Median
$77.62
Typical High
$93.33
Aetna
Setting
Professional
Modifier
56 · Pre-op care only
Typical Low
$51.29
Median
$51.29
Typical High
$61.66

Where Missouri sits

The same service costs 1.6 times more in Arizona than in Nebraska. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 23rd of 51

$513

AZ $813NE $501

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.