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Burosumab-twza Injection

Alabama rates for HCPCS J0584 · Crysvita

Injection, burosumab-twza, 1 mg

Rates data updated October 2026.

How much does Crysvita (burosumab) cost?

$23,442per mg

Typical negotiated rate. In Alabama, October 2026.

Insurers have agreed to pay about $23,442 for each mg of this drug. The price depends on where it is billed: about $513 from a physician practice, and about $23,442 from a hospital or other facility.

Work out the cost of a dose

This drug is priced per mg. Enter the amount given to see what insurers have agreed to pay for it.

mg
In a doctor's office or clinic
$513
At a hospital outpatient department
$23,442

The same drug, in the same amount, costs 4471% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$513$501 to $513
FacilityA hospital or hospital-owned outpatient department$23,442$23,442 to $23,442

How much rates vary

Facilitymedian $23,442 · 10th to 90th $661 to $23,442Professionalmedian $513 · 10th to 90th $501 to $513
$500$1K$2K$5K$10K$20Kfacility $23,442professional $513

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
None
Typical Low
$512.86
Median
$512.86
Typical High
$512.86
BCBS
Setting
Facility
Modifier
None
Typical Low
$23,442.29
Median
$23,442.29
Typical High
$23,442.29
BCBS
Setting
Professional
Modifier
12
Typical Low
$512.86
Median
$512.86
Typical High
$512.86
Cigna
Setting
Facility
Modifier
None
Typical Low
$512.86
Median
$524.81
Typical High
$660.69
Cigna
Setting
Professional
Modifier
None
Typical Low
$512.86
Median
$512.86
Typical High
$512.86
United
Setting
Facility
Modifier
None
Typical Low
$512.86
Median
$512.86
Typical High
$512.86
United
Setting
Professional
Modifier
None
Typical Low
$501.19
Median
$501.19
Typical High
$501.19
4 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$257.04
Median
$257.04
Typical High
$257.04
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$102.33
Median
$102.33
Typical High
$102.33
Aetna
Setting
Professional
Modifier
55 · Aftercare only
Typical Low
$77.62
Median
$77.62
Typical High
$77.62
Aetna
Setting
Professional
Modifier
56 · Pre-op care only
Typical Low
$51.29
Median
$51.29
Typical High
$51.29

Where Alabama sits

The same service costs 46.8 times more in Alabama than in Rhode Island. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Alabama· 1st of 51

$23,442

AL $23,442RI $501

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.