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Cerliponase Alfa Injection

Pennsylvania rates for HCPCS J0567 · Brineura

Injection, cerliponase alfa, 1 mg

Rates data updated July 2026.

How much does Brineura (cerliponase alfa) cost?

$123per mg

Typical negotiated rate. In Pennsylvania, July 2026.

Insurers have agreed to pay about $123 for each mg of this drug. The price depends on where it is billed: about $123 from a physician practice, and about $182 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

Work out the cost of a dose

This drug is priced per mg. Enter the amount given to see what insurers have agreed to pay for it.

mg
In a doctor's office or clinic
$123
At a hospital outpatient department
$182

The same drug, in the same amount, costs 48% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$123$123 to $123
FacilityA hospital or hospital-owned outpatient department$182$123 to $316

How much rates vary

Facilitymedian $182 · 10th to 90th $123 to $355Professionalmedian $123 · 10th to 90th $123 to $123
$100$200$500$1K$2K$5Kfacility $182professional $123

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$123.03
Median
$186.21
Typical High
$354.81
Aetna
Setting
Professional
Modifier
Global
Typical Low
$123.03
Median
$123.03
Typical High
$123.03
Capital Blue Cross
Setting
Facility
Modifier
Global
Typical Low
$102.33
Median
$120.23
Typical High
$8,511.38
Capital Blue Cross
Setting
Professional
Modifier
Global
Typical Low
$120.23
Median
$120.23
Typical High
$120.23
Cigna
Setting
Facility
Modifier
Global
Typical Low
$123.03
Median
$426.58
Typical High
$457.09
Cigna
Setting
Professional
Modifier
Global
Typical Low
$123.03
Median
$123.03
Typical High
$123.03
Martin's Point
Setting
Facility
Modifier
Global
Typical Low
$123.03
Median
$181.97
Typical High
$338.84
Martin's Point
Setting
Professional
Modifier
Global
Typical Low
$123.03
Median
$123.03
Typical High
$316.23
United
Setting
Facility
Modifier
Global
Typical Low
$120.23
Median
$120.23
Typical High
$120.23
United
Setting
Professional
Modifier
Global
Typical Low
$120.23
Median
$120.23
Typical High
$165.96

Where Pennsylvania sits

The same service costs 1.7 times more in Colorado than in Kentucky. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Pennsylvania· 26th of 51

$123

CO $200KY $115

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.