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Cerliponase Alfa Injection

Missouri rates for HCPCS J0567 · Brineura

Injection, cerliponase alfa, 1 mg

Rates data updated July 2026.

How much does Brineura (cerliponase alfa) cost?

$120per mg

Typical negotiated rate. In Missouri, July 2026.

Insurers have agreed to pay about $120 for each mg of this drug. The price depends on where it is billed: about $115 from a physician practice, and about $138 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

Work out the cost of a dose

This drug is priced per mg. Enter the amount given to see what insurers have agreed to pay for it.

mg
In a doctor's office or clinic
$115
At a hospital outpatient department
$138

The same drug, in the same amount, costs 20% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$115$115 to $145
FacilityA hospital or hospital-owned outpatient department$138$120 to $151

How much rates vary

Facilitymedian $138 · 10th to 90th $115 to $316Professionalmedian $115 · 10th to 90th $107 to $145
$100$200$500facility $138professional $115

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$114.82
Median
$144.54
Typical High
$199.53
Aetna
Setting
Professional
Modifier
Global
Typical Low
$114.82
Median
$114.82
Typical High
$199.53
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$120.23
Median
$128.82
Typical High
$426.58
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$107.15
Median
$107.15
Typical High
$144.54
Cigna
Setting
Facility
Modifier
Global
Typical Low
$131.83
Median
$144.54
Typical High
$151.36
Cigna
Setting
Professional
Modifier
Global
Typical Low
$123.03
Median
$123.03
Typical High
$123.03
Medica
Setting
Facility
Modifier
Global
Typical Low
$112.20
Median
$138.04
Typical High
$501.19
Medica
Setting
Professional
Modifier
Global
Typical Low
$87.10
Median
$117.49
Typical High
$134.90
United
Setting
Facility
Modifier
Global
Typical Low
$120.23
Median
$120.23
Typical High
$190.55
United
Setting
Professional
Modifier
Global
Typical Low
$102.33
Median
$120.23
Typical High
$138.04

Where Missouri sits

The same service costs 1.7 times more in Colorado than in Kentucky. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 40th of 51

$120

CO $200KY $115

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.