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Cerliponase Alfa Injection

Indiana rates for HCPCS J0567 · Brineura

Injection, cerliponase alfa, 1 mg

Rates data updated October 2026.

How much does Brineura (cerliponase alfa) cost?

$120per mg

Typical negotiated rate. In Indiana, October 2026.

Insurers have agreed to pay about $120 for each mg of this drug. The price depends on where it is billed: about $120 from a physician practice, and about $178 from a hospital or other facility.

Work out the cost of a dose

This drug is priced per mg. Enter the amount given to see what insurers have agreed to pay for it.

mg
In a doctor's office or clinic
$120
At a hospital outpatient department
$178

The same drug, in the same amount, costs 48% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$120$89.13 to $123
FacilityA hospital or hospital-owned outpatient department$178$123 to $240

How much rates vary

Facilitymedian $178 · 10th to 90th $115 to $339Professionalmedian $120 · 10th to 90th $89 to $182
$100$200$500$1Kfacility $178professional $120

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$114.82
Median
$114.82
Typical High
$229.09
Aetna
Setting
Professional
Modifier
None
Typical Low
$114.82
Median
$114.82
Typical High
$114.82
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$120.23
Median
$177.83
Typical High
$239.88
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$89.13
Median
$89.13
Typical High
$162.18
Cigna
Setting
Facility
Modifier
None
Typical Low
$138.04
Median
$338.84
Typical High
$354.81
Cigna
Setting
Professional
Modifier
None
Typical Low
$120.23
Median
$120.23
Typical High
$123.03
Physicians Health Plan of Northern Indiana
Setting
Facility
Modifier
None
Typical Low
$72.44
Median
$186.21
Typical High
$954.99
United
Setting
Professional
Modifier
None
Typical Low
$120.23
Median
$120.23
Typical High
$380.19
4 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$57.54
Median
$57.54
Typical High
$57.54
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$22.91
Median
$22.91
Typical High
$22.91
Aetna
Setting
Professional
Modifier
55 · Aftercare only
Typical Low
$17.38
Median
$17.38
Typical High
$17.38
Aetna
Setting
Professional
Modifier
56 · Pre-op care only
Typical Low
$11.48
Median
$11.48
Typical High
$11.48

Where Indiana sits

The same service costs 1.7 times more in Arizona than in Hawaii. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Indiana· 34th of 51

$120

AZ $195HI $112

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.