go back

Cerliponase Alfa Injection

Colorado rates for HCPCS J0567 · Brineura

Injection, cerliponase alfa, 1 mg

Rates data updated October 2026.

How much does Brineura (cerliponase alfa) cost?

$148per mg

Typical negotiated rate. In Colorado, October 2026.

Insurers have agreed to pay about $148 for each mg of this drug. The price depends on where it is billed: about $123 from a physician practice, and about $200 from a hospital or other facility.

Work out the cost of a dose

This drug is priced per mg. Enter the amount given to see what insurers have agreed to pay for it.

mg
In a doctor's office or clinic
$123
At a hospital outpatient department
$200

The same drug, in the same amount, costs 62% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$123$120 to $123
FacilityA hospital or hospital-owned outpatient department$200$148 to $229

How much rates vary

Facilitymedian $200 · 10th to 90th $126 to $347Professionalmedian $123 · 10th to 90th $115 to $123
$200$500facility $200professional $123

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$114.82
Median
$229.09
Typical High
$489.78
Aetna
Setting
Professional
Modifier
None
Typical Low
$114.82
Median
$114.82
Typical High
$229.09
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$128.82
Median
$204.17
Typical High
$346.74
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$123.03
Median
$123.03
Typical High
$123.03
Cigna
Setting
Facility
Modifier
None
Typical Low
$123.03
Median
$123.03
Typical High
$123.03
Cigna
Setting
Professional
Modifier
None
Typical Low
$123.03
Median
$123.03
Typical High
$123.03
Denver HMP
Setting
Facility
Modifier
None
Typical Low
$114.82
Median
$114.82
Typical High
$165.96
Select Health
Setting
Professional
Modifier
None
Typical Low
$131.83
Median
$131.83
Typical High
$131.83
United
Setting
Facility
Modifier
None
Typical Low
$123.03
Median
$123.03
Typical High
$123.03
United
Setting
Professional
Modifier
None
Typical Low
$120.23
Median
$120.23
Typical High
$120.23
4 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$57.54
Median
$57.54
Typical High
$114.82
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$22.91
Median
$22.91
Typical High
$45.71
Aetna
Setting
Professional
Modifier
55 · Aftercare only
Typical Low
$17.38
Median
$17.38
Typical High
$34.67
Aetna
Setting
Professional
Modifier
56 · Pre-op care only
Typical Low
$11.48
Median
$11.48
Typical High
$22.91

Where Colorado sits

The same service costs 1.7 times more in Arizona than in Hawaii. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Colorado· 3rd of 51

$148

AZ $195HI $112

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.