go back

Cerliponase Alfa Injection

California rates for HCPCS J0567 · Brineura

Injection, cerliponase alfa, 1 mg

Rates data updated October 2026.

How much does Brineura (cerliponase alfa) cost?

$123per mg

Typical negotiated rate. In California, October 2026.

Insurers have agreed to pay about $123 for each mg of this drug. The price depends on where it is billed: about $123 from a physician practice, and about $166 from a hospital or other facility.

Work out the cost of a dose

This drug is priced per mg. Enter the amount given to see what insurers have agreed to pay for it.

mg
In a doctor's office or clinic
$123
At a hospital outpatient department
$166

The same drug, in the same amount, costs 35% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$123$120 to $135
FacilityA hospital or hospital-owned outpatient department$166$123 to $245

How much rates vary

Facilitymedian $166 · 10th to 90th $87 to $331Professionalmedian $123 · 10th to 90th $120 to $240
$100$200$500facility $166professional $123

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$120.23
Median
$120.23
Typical High
$213.80
Aetna
Setting
Professional
Modifier
None
Typical Low
$120.23
Median
$120.23
Typical High
$120.23
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$128.82
Median
$204.17
Typical High
$416.87
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$97.72
Median
$123.03
Typical High
$234.42
Blue Shield
Setting
Facility
Modifier
None
Typical Low
$75.86
Median
$123.03
Typical High
$177.83
Blue Shield
Setting
Professional
Modifier
None
Typical Low
$120.23
Median
$141.25
Typical High
$295.12
Central California Alliance for Health
Setting
Professional
Modifier
None
Typical Low
$120.23
Median
$154.88
Typical High
$177.83
Cigna
Setting
Facility
Modifier
None
Typical Low
$123.03
Median
$245.47
Typical High
$371.54
Cigna
Setting
Professional
Modifier
None
Typical Low
$123.03
Median
$123.03
Typical High
$123.03
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$407.38
Median
$407.38
Typical High
$407.38
Providence
Setting
Facility
Modifier
None
Typical Low
$123.03
Median
$169.82
Typical High
$331.13
Providence
Setting
Professional
Modifier
None
Typical Low
$123.03
Median
$123.03
Typical High
$123.03
United
Setting
Facility
Modifier
None
Typical Low
$123.03
Median
$123.03
Typical High
$316.23
United
Setting
Professional
Modifier
None
Typical Low
$120.23
Median
$120.23
Typical High
$323.59
4 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$58.88
Median
$58.88
Typical High
$58.88
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$23.99
Median
$23.99
Typical High
$23.99
Aetna
Setting
Professional
Modifier
55 · Aftercare only
Typical Low
$17.78
Median
$17.78
Typical High
$17.78
Aetna
Setting
Professional
Modifier
56 · Pre-op care only
Typical Low
$12.02
Median
$12.02
Typical High
$12.02

Where California sits

The same service costs 1.7 times more in Arizona than in Hawaii. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

California· 16th of 51

$123

AZ $195HI $112

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.