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Alpha 1 Proteinase Inhibitor (Glassia) Injection

Massachusetts rates for HCPCS J0257

Injection, alpha 1 proteinase inhibitor (human), (GLASSIA), 10 mg

Rates data updated October 2026.

How much does Glassia (alpha.1-proteinase inhibitor human) cost?

$5.62per 10 mg

Typical negotiated rate. In Massachusetts, October 2026.

Insurers have agreed to pay about $5.62 for each 10 mg of this drug. The price depends on where it is billed: about $5.62 from a physician practice, and about $7.41 from a hospital or other facility.

Work out the cost of a dose

This drug is priced per 10 mg. Enter the amount given to see what insurers have agreed to pay for it.

mg
In a doctor's office or clinic
$5.62
At a hospital outpatient department
$7.41

The same drug, in the same amount, costs 32% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 9 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$5.62$5.62 to $6.76
FacilityA hospital or hospital-owned outpatient department$7.41$5.62 to $10.72

How much rates vary

Facilitymedian $7 · 10th to 90th $6 to $15Professionalmedian $6 · 10th to 90th $6 to $9
$10$20facility $7professional $6

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$5.62
Median
$5.62
Typical High
$5.62
Aetna
Setting
Professional
Modifier
None
Typical Low
$5.62
Median
$5.62
Typical High
$5.62
AllWays Health Partners
Setting
Facility
Modifier
None
Typical Low
$5.13
Median
$5.62
Typical High
$18.20
AllWays Health Partners
Setting
Professional
Modifier
None
Typical Low
$5.62
Median
$5.62
Typical High
$8.51
BCBS Massachusetts
Setting
Facility
Modifier
None
Typical Low
$5.62
Median
$6.31
Typical High
$11.48
Cigna
Setting
Facility
Modifier
None
Typical Low
$7.24
Median
$11.75
Typical High
$23.99
Cigna
Setting
Professional
Modifier
None
Typical Low
$5.62
Median
$5.62
Typical High
$6.92
Fallon Health
Setting
Facility
Modifier
None
Typical Low
$5.62
Median
$7.41
Typical High
$8.71
Harvard Pilgrim
Setting
Professional
Modifier
None
Typical Low
$5.62
Median
$5.62
Typical High
$9.55
Mass General Brigham
Setting
Facility
Modifier
None
Typical Low
$5.13
Median
$5.62
Typical High
$18.20
Mass General Brigham
Setting
Professional
Modifier
None
Typical Low
$5.62
Median
$5.62
Typical High
$8.51
United
Setting
Facility
Modifier
None
Typical Low
$5.62
Median
$5.62
Typical High
$5.62
United
Setting
Professional
Modifier
None
Typical Low
$5.62
Median
$5.62
Typical High
$9.55
Well Sense
Setting
Facility
Modifier
None
Typical Low
$6.17
Median
$8.13
Typical High
$12.88
Well Sense
Setting
Professional
Modifier
None
Typical Low
$5.62
Median
$5.62
Typical High
$6.76
4 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$2.82
Median
$2.82
Typical High
$2.82
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$1.12
Median
$1.12
Typical High
$1.12
Aetna
Setting
Professional
Modifier
55 · Aftercare only
Typical Low
$0.83
Median
$0.83
Typical High
$0.83
Aetna
Setting
Professional
Modifier
56 · Pre-op care only
Typical Low
$0.56
Median
$0.56
Typical High
$0.56

Where Massachusetts sits

The same service costs 1.7 times more in Arizona than in Vermont. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Massachusetts· 36th of 51

$5.62

AZ $9.55VT $5.62

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.