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Alpha 1-proteinase Inhibitor Injection

Massachusetts rates for HCPCS J0256 · Zemaira, Aralast NP, Prolastin-C Liquid

Injection, alpha 1-proteinase inhibitor (human), not otherwise specified, 10 mg

Rates data updated July 2026.

How much does Alpha 1-proteinase Inhibitor Injection cost?

$2,457per dose

One 4,790 mg dose, at the doctor's office rate. In Massachusetts, July 2026.

Negotiated ratewhat insurers pay per 10 mg of the drug
$5.13 / 10 mg
Average doseacross Medicare claims, discarded units included
× 4,790 mg
One dosedrug only; giving it and the visit are billed separately
$2,457

Work out the cost of a dose

This drug is priced per 10 mg. Enter the amount given to see what insurers have agreed to pay for it. Prefilled with the average administration in Medicare claims, discarded units included.

mg
In a doctor's office or clinic
$2,457
At a hospital outpatient department
$2,953

The same drug, in the same amount, costs 20% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 9 insurance carriers under federal price transparency rules.

Where the price changes

Given atPer 10 mgPer 4,790 mg dose
Doctor's office or clinic$5.13$2,457
Hospital outpatient department$6.17$2,953

How much rates vary

Facilitymedian $6 · 10th to 90th $5 to $15Professionalmedian $5 · 10th to 90th $5 to $9
$10$100$1Kfacility $6professional $5

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$5.13
Median
$7.08
Typical High
$13.49
Aetna
Setting
Professional
Modifier
Global
Typical Low
$5.13
Median
$5.13
Typical High
$9.77
AllWays Health Partners
Setting
Facility
Modifier
Global
Typical Low
$4.57
Median
$15.14
Typical High
$309.03
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$5.13
Median
$5.37
Typical High
$6.61
BCBS
Setting
Facility
Modifier
Global
Typical Low
$5.13
Median
$5.13
Typical High
$10.23
Cigna
Setting
Facility
Modifier
Global
Typical Low
$6.61
Median
$10.72
Typical High
$22.39
Cigna
Setting
Professional
Modifier
Global
Typical Low
$5.13
Median
$5.13
Typical High
$6.17
Fallon Health
Setting
Facility
Modifier
Global
Typical Low
$5.13
Median
$7.41
Typical High
$6,918.31
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$5.13
Median
$5.13
Typical High
$8.51
Health New England
Setting
Facility
Modifier
Global
Typical Low
$4,365.16
Median
$4,365.16
Typical High
$4,365.16
Mass General Brigham
Setting
Facility
Modifier
Global
Typical Low
$4.57
Median
$15.14
Typical High
$309.03
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$5.13
Median
$5.37
Typical High
$6.61
United
Setting
Facility
Modifier
Global
Typical Low
$5.13
Median
$5.13
Typical High
$10.96
United
Setting
Professional
Modifier
Global
Typical Low
$5.13
Median
$5.37
Typical High
$6.46

Where Massachusetts sits

The same service costs 2.4 times more in Delaware than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Massachusetts· 46th of 51

$5.13

DE $12.30AL $5.13

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.