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Lumasiran Injection

Massachusetts rates for HCPCS J0224 · Oxlumo

Injection, lumasiran, 0.5 mg

Rates data updated October 2026.

How much does Oxlumo (lumasiran) cost?

$339per 0.5 mg

Typical negotiated rate. In Massachusetts, October 2026.

Insurers have agreed to pay about $339 for each 0.5 mg of this drug. The price depends on where it is billed: about $339 from a physician practice, and about $437 from a hospital or other facility.

Work out the cost of a dose

This drug is priced per 0.5 mg. Enter the amount given to see what insurers have agreed to pay for it.

mg
In a doctor's office or clinic
$339
At a hospital outpatient department
$437

The same drug, in the same amount, costs 29% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 9 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$339$331 to $339
FacilityA hospital or hospital-owned outpatient department$437$339 to $603

How much rates vary

Facilitymedian $437 · 10th to 90th $331 to $933Professionalmedian $339 · 10th to 90th $331 to $490
$100$200$500$1Kfacility $437professional $339

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$338.84
Median
$338.84
Typical High
$338.84
Aetna
Setting
Professional
Modifier
None
Typical Low
$338.84
Median
$338.84
Typical High
$338.84
AllWays Health Partners
Setting
Facility
Modifier
None
Typical Low
$309.03
Median
$371.54
Typical High
$1,096.48
AllWays Health Partners
Setting
Professional
Modifier
None
Typical Low
$331.13
Median
$331.13
Typical High
$489.78
BCBS Massachusetts
Setting
Facility
Modifier
None
Typical Low
$338.84
Median
$380.19
Typical High
$691.83
Cigna
Setting
Facility
Modifier
None
Typical Low
$436.52
Median
$707.95
Typical High
$1,479.11
Cigna
Setting
Professional
Modifier
None
Typical Low
$338.84
Median
$338.84
Typical High
$398.11
Fallon Health
Setting
Facility
Modifier
None
Typical Low
$331.13
Median
$436.52
Typical High
$512.86
Harvard Pilgrim
Setting
Professional
Modifier
None
Typical Low
$331.13
Median
$338.84
Typical High
$549.54
Mass General Brigham
Setting
Facility
Modifier
None
Typical Low
$309.03
Median
$371.54
Typical High
$1,096.48
Mass General Brigham
Setting
Professional
Modifier
None
Typical Low
$331.13
Median
$331.13
Typical High
$489.78
United
Setting
Facility
Modifier
None
Typical Low
$338.84
Median
$338.84
Typical High
$338.84
United
Setting
Professional
Modifier
None
Typical Low
$331.13
Median
$331.13
Typical High
$549.54
Well Sense
Setting
Facility
Modifier
None
Typical Low
$363.08
Median
$489.78
Typical High
$776.25
Well Sense
Setting
Professional
Modifier
None
Typical Low
$338.84
Median
$338.84
Typical High
$407.38
4 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$169.82
Median
$169.82
Typical High
$169.82
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$67.61
Median
$67.61
Typical High
$67.61
Aetna
Setting
Professional
Modifier
55 · Aftercare only
Typical Low
$50.12
Median
$50.12
Typical High
$50.12
Aetna
Setting
Professional
Modifier
56 · Pre-op care only
Typical Low
$33.88
Median
$33.88
Typical High
$33.88

Where Massachusetts sits

The same service costs 1.5 times more in Arizona than in Rhode Island. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Massachusetts· 35th of 51

$339

AZ $513RI $331

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.