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Lumasiran Injection

California rates for HCPCS J0224 · Oxlumo

Injection, lumasiran, 0.5 mg

Rates data updated October 2026.

How much does Oxlumo (lumasiran) cost?

$339per 0.5 mg

Typical negotiated rate. In California, October 2026.

Insurers have agreed to pay about $339 for each 0.5 mg of this drug. The price depends on where it is billed: about $339 from a physician practice, and about $479 from a hospital or other facility.

Work out the cost of a dose

This drug is priced per 0.5 mg. Enter the amount given to see what insurers have agreed to pay for it.

mg
In a doctor's office or clinic
$339
At a hospital outpatient department
$479

The same drug, in the same amount, costs 41% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 9 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$339$331 to $468
FacilityA hospital or hospital-owned outpatient department$479$339 to $676

How much rates vary

Facilitymedian $479 · 10th to 90th $95 to $933Professionalmedian $339 · 10th to 90th $331 to $871
$100$200$500$1Kfacility $479professional $339

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$338.84
Median
$338.84
Typical High
$588.84
Aetna
Setting
Professional
Modifier
None
Typical Low
$338.84
Median
$338.84
Typical High
$338.84
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$363.08
Median
$562.34
Typical High
$1,148.15
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$316.23
Median
$331.13
Typical High
$891.25
Blue Shield
Setting
Facility
Modifier
None
Typical Low
$75.86
Median
$331.13
Typical High
$478.63
Blue Shield
Setting
Professional
Modifier
None
Typical Low
$338.84
Median
$407.38
Typical High
$912.01
Central California Alliance for Health
Setting
Professional
Modifier
None
Typical Low
$302.00
Median
$371.54
Typical High
$501.19
Cigna
Setting
Facility
Modifier
None
Typical Low
$346.74
Median
$616.60
Typical High
$851.14
Cigna
Setting
Professional
Modifier
None
Typical Low
$338.84
Median
$338.84
Typical High
$338.84
Contra Costa Health
Setting
Professional
Modifier
None
Typical Low
$363.08
Median
$363.08
Typical High
$363.08
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$302.00
Median
$407.38
Typical High
$891.25
Providence
Setting
Facility
Modifier
None
Typical Low
$338.84
Median
$602.56
Typical High
$933.25
Providence
Setting
Professional
Modifier
None
Typical Low
$338.84
Median
$338.84
Typical High
$346.74
United
Setting
Facility
Modifier
None
Typical Low
$338.84
Median
$338.84
Typical High
$338.84
United
Setting
Professional
Modifier
None
Typical Low
$331.13
Median
$331.13
Typical High
$870.96
4 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$169.82
Median
$169.82
Typical High
$169.82
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$67.61
Median
$67.61
Typical High
$67.61
Aetna
Setting
Professional
Modifier
55 · Aftercare only
Typical Low
$50.12
Median
$51.29
Typical High
$51.29
Aetna
Setting
Professional
Modifier
56 · Pre-op care only
Typical Low
$33.88
Median
$33.88
Typical High
$33.88

Where California sits

The same service costs 1.5 times more in Arizona than in Rhode Island. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

California· 30th of 51

$339

AZ $513RI $331

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.