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Alglucosidase Alfa (Lumizyme) Injection

South Dakota rates for HCPCS J0221

Injection, alglucosidase alfa, (Lumizyme), 10 mg

Rates data updated October 2026.

How much does Lumizyme (alglucosidase alfa) cost?

$209per 10 mg

Typical negotiated rate. In South Dakota, October 2026.

Insurers have agreed to pay about $209 for each 10 mg of this drug. The price depends on where it is billed: about $214 from a physician practice, and about $209 from a hospital or other facility.

Work out the cost of a dose

This drug is priced per 10 mg. Enter the amount given to see what insurers have agreed to pay for it.

mg
In a doctor's office or clinic
$214
At a hospital outpatient department
$209

The same drug, in the same amount, costs 2% less at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$214$209 to $229
FacilityA hospital or hospital-owned outpatient department$209$209 to $257

How much rates vary

Facilitymedian $209 · 10th to 90th $209 to $347Professionalmedian $214 · 10th to 90th $209 to $269
$200$500facility $209professional $214

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$208.93
Median
$208.93
Typical High
$208.93
Aetna
Setting
Professional
Modifier
None
Typical Low
$208.93
Median
$208.93
Typical High
$208.93
Cigna
Setting
Facility
Modifier
None
Typical Low
$208.93
Median
$208.93
Typical High
$208.93
Cigna
Setting
Professional
Modifier
None
Typical Low
$213.80
Median
$213.80
Typical High
$269.15
Medica
Setting
Facility
Modifier
None
Typical Low
$204.17
Median
$346.74
Typical High
$346.74
Medica
Setting
Professional
Modifier
None
Typical Low
$173.78
Median
$208.93
Typical High
$229.09
Midlands
Setting
Professional
Modifier
None
Typical Low
$245.47
Median
$245.47
Typical High
$245.47
Sanford Health Plan
Setting
Professional
Modifier
None
Typical Low
$208.93
Median
$229.09
Typical High
$229.09
United
Setting
Professional
Modifier
None
Typical Low
$208.93
Median
$208.93
Typical High
$229.09
Wellmark
Setting
Facility
Modifier
None
Typical Low
$208.93
Median
$208.93
Typical High
$208.93
Wellmark
Setting
Professional
Modifier
None
Typical Low
$208.93
Median
$208.93
Typical High
$208.93

Where South Dakota sits

The same service costs 1.6 times more in Arizona than in New Jersey. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Dakota· 50th of 51

$209

AZ $339NJ $209

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.