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Alglucosidase Alfa (Lumizyme) Injection

Pennsylvania rates for HCPCS J0221

Injection, alglucosidase alfa, (Lumizyme), 10 mg

Rates data updated October 2026.

How much does Lumizyme (alglucosidase alfa) cost?

$214per 10 mg

Typical negotiated rate. In Pennsylvania, October 2026.

Insurers have agreed to pay about $214 for each 10 mg of this drug. The price depends on where it is billed: about $209 from a physician practice, and about $245 from a hospital or other facility.

Work out the cost of a dose

This drug is priced per 10 mg. Enter the amount given to see what insurers have agreed to pay for it.

mg
In a doctor's office or clinic
$209
At a hospital outpatient department
$245

The same drug, in the same amount, costs 17% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$209$209 to $214
FacilityA hospital or hospital-owned outpatient department$245$209 to $302

How much rates vary

Facilitymedian $245 · 10th to 90th $209 to $776Professionalmedian $209 · 10th to 90th $209 to $234
$200$500facility $245professional $209

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$208.93
Median
$316.23
Typical High
$549.54
Aetna
Setting
Professional
Modifier
None
Typical Low
$208.93
Median
$213.80
Typical High
$213.80
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$104.71
Median
$107.15
Typical High
$107.15
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$42.66
Median
$42.66
Typical High
$42.66
Aetna
Setting
Professional
Modifier
55 · Aftercare only
Typical Low
$31.62
Median
$32.36
Typical High
$32.36
Aetna
Setting
Professional
Modifier
56 · Pre-op care only
Typical Low
$20.89
Median
$21.38
Typical High
$21.38
Capital Blue Cross
Setting
Facility
Modifier
None
Typical Low
$199.53
Median
$229.09
Typical High
$269.15
Capital Blue Cross
Setting
Professional
Modifier
None
Typical Low
$218.78
Median
$218.78
Typical High
$229.09
Cigna
Setting
Facility
Modifier
None
Typical Low
$208.93
Median
$354.81
Typical High
$812.83
Cigna
Setting
Professional
Modifier
None
Typical Low
$208.93
Median
$208.93
Typical High
$208.93
Geisinger
Setting
Facility
Modifier
None
Typical Low
$208.93
Median
$208.93
Typical High
$208.93
Geisinger
Setting
Professional
Modifier
None
Typical Low
$316.23
Median
$316.23
Typical High
$380.19
Martin's Point
Setting
Facility
Modifier
None
Typical Low
$208.93
Median
$316.23
Typical High
$549.54
Martin's Point
Setting
Professional
Modifier
None
Typical Low
$208.93
Median
$213.80
Typical High
$213.80
Martin's Point
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$104.71
Median
$107.15
Typical High
$107.15
Martin's Point
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$42.66
Median
$42.66
Typical High
$42.66
Martin's Point
Setting
Professional
Modifier
55 · Aftercare only
Typical Low
$31.62
Median
$32.36
Typical High
$32.36
Martin's Point
Setting
Professional
Modifier
56 · Pre-op care only
Typical Low
$20.89
Median
$21.38
Typical High
$21.38
UPMC Health Plan
Setting
Facility
Modifier
None
Typical Low
$190.55
Median
$245.47
Typical High
$257.04
UPMC Health Plan
Setting
Professional
Modifier
None
Typical Low
$190.55
Median
$190.55
Typical High
$218.78
United
Setting
Facility
Modifier
None
Typical Low
$208.93
Median
$208.93
Typical High
$208.93
United
Setting
Professional
Modifier
None
Typical Low
$208.93
Median
$208.93
Typical High
$288.40

Where Pennsylvania sits

The same service costs 1.6 times more in Arizona than in New Jersey. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Pennsylvania· 19th of 51

$214

AZ $339NJ $209

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.