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Alglucosidase Alfa (Lumizyme) Injection

Missouri rates for HCPCS J0221

Injection, alglucosidase alfa, (Lumizyme), 10 mg

Rates data updated July 2026.

How much does Lumizyme (alglucosidase alfa) cost?

$214per 10 mg

Typical negotiated rate. In Missouri, July 2026.

Insurers have agreed to pay about $214 for each 10 mg of this drug. The price depends on where it is billed: about $214 from a physician practice, and about $224 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

Work out the cost of a dose

This drug is priced per 10 mg. Enter the amount given to see what insurers have agreed to pay for it.

mg
In a doctor's office or clinic
$214
At a hospital outpatient department
$224

The same drug, in the same amount, costs 5% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$214$209 to $240
FacilityA hospital or hospital-owned outpatient department$224$209 to $257

How much rates vary

Facilitymedian $224 · 10th to 90th $209 to $550Professionalmedian $214 · 10th to 90th $209 to $251
$200$500$1Kfacility $224professional $214

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$208.93
Median
$213.80
Typical High
$295.12
Aetna
Setting
Professional
Modifier
Global
Typical Low
$208.93
Median
$213.80
Typical High
$295.12
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$208.93
Median
$223.87
Typical High
$724.44
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$208.93
Median
$208.93
Typical High
$245.47
Cigna
Setting
Facility
Modifier
Global
Typical Low
$223.87
Median
$257.04
Typical High
$602.56
Cigna
Setting
Professional
Modifier
Global
Typical Low
$208.93
Median
$208.93
Typical High
$208.93
Medica
Setting
Facility
Modifier
Global
Typical Low
$199.53
Median
$239.88
Typical High
$1,000.00
Medica
Setting
Professional
Modifier
Global
Typical Low
$154.88
Median
$208.93
Typical High
$239.88
United
Setting
Facility
Modifier
Global
Typical Low
$169.82
Median
$208.93
Typical High
$302.00
United
Setting
Professional
Modifier
Global
Typical Low
$177.83
Median
$208.93
Typical High
$239.88

Where Missouri sits

The same service costs 2.3 times more in Delaware than in Maryland. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 31st of 51

$214

DE $490MD $209

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.