go back

Alglucosidase Alfa (Lumizyme) Injection

Massachusetts rates for HCPCS J0221

Injection, alglucosidase alfa, (Lumizyme), 10 mg

Rates data updated July 2026.

How much does Lumizyme (alglucosidase alfa) cost?

$209per 10 mg

Typical negotiated rate. In Massachusetts, July 2026.

Insurers have agreed to pay about $209 for each 10 mg of this drug. The price depends on where it is billed: about $209 from a physician practice, and about $245 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

Work out the cost of a dose

This drug is priced per 10 mg. Enter the amount given to see what insurers have agreed to pay for it.

mg
In a doctor's office or clinic
$209
At a hospital outpatient department
$245

The same drug, in the same amount, costs 17% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$209$209 to $214
FacilityA hospital or hospital-owned outpatient department$245$209 to $339

How much rates vary

Facilitymedian $245 · 10th to 90th $209 to $562Professionalmedian $209 · 10th to 90th $209 to $331
$200$500$1K$2K$5Kfacility $245professional $209

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$208.93
Median
$288.40
Typical High
$549.54
Aetna
Setting
Professional
Modifier
Global
Typical Low
$208.93
Median
$208.93
Typical High
$213.80
AllWays Health Partners
Setting
Facility
Modifier
Global
Typical Low
$186.21
Median
$234.42
Typical High
$691.83
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$208.93
Median
$208.93
Typical High
$257.04
BCBS
Setting
Facility
Modifier
Global
Typical Low
$208.93
Median
$208.93
Typical High
$416.87
Cigna
Setting
Facility
Modifier
Global
Typical Low
$269.15
Median
$436.52
Typical High
$891.25
Cigna
Setting
Professional
Modifier
Global
Typical Low
$208.93
Median
$208.93
Typical High
$251.19
Fallon Health
Setting
Facility
Modifier
Global
Typical Low
$208.93
Median
$302.00
Typical High
$6,918.31
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$208.93
Median
$208.93
Typical High
$346.74
Mass General Brigham
Setting
Facility
Modifier
Global
Typical Low
$186.21
Median
$234.42
Typical High
$691.83
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$208.93
Median
$208.93
Typical High
$257.04
United
Setting
Facility
Modifier
Global
Typical Low
$208.93
Median
$208.93
Typical High
$446.68
United
Setting
Professional
Modifier
Global
Typical Low
$208.93
Median
$208.93
Typical High
$218.78

Where Massachusetts sits

The same service costs 2.3 times more in Delaware than in Maryland. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Massachusetts· 49th of 51

$209

DE $490MD $209

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.