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Alglucosidase Alfa (Lumizyme) Injection

Colorado rates for HCPCS J0221

Injection, alglucosidase alfa, (Lumizyme), 10 mg

Rates data updated October 2026.

How much does Lumizyme (alglucosidase alfa) cost?

$263per 10 mg

Typical negotiated rate. In Colorado, October 2026.

Insurers have agreed to pay about $263 for each 10 mg of this drug. The price depends on where it is billed: about $209 from a physician practice, and about $316 from a hospital or other facility.

Work out the cost of a dose

This drug is priced per 10 mg. Enter the amount given to see what insurers have agreed to pay for it.

mg
In a doctor's office or clinic
$209
At a hospital outpatient department
$316

The same drug, in the same amount, costs 51% more at a hospital than at a doctor's office.

Drug cost only. Giving the drug, the visit itself and any monitoring are billed on their own codes. We do not publish dosing guidance: use the amount from your own prescription or treatment plan.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$209$209 to $209
FacilityA hospital or hospital-owned outpatient department$316$240 to $389

How much rates vary

Facilitymedian $316 · 10th to 90th $224 to $631Professionalmedian $209 · 10th to 90th $209 to $234
$200$500$1Kfacility $316professional $209

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$208.93
Median
$416.87
Typical High
$891.25
Aetna
Setting
Professional
Modifier
None
Typical Low
$208.93
Median
$208.93
Typical High
$416.87
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$229.09
Median
$331.13
Typical High
$676.08
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$208.93
Median
$208.93
Typical High
$208.93
Cigna
Setting
Facility
Modifier
None
Typical Low
$213.80
Median
$239.88
Typical High
$302.00
Cigna
Setting
Professional
Modifier
None
Typical Low
$208.93
Median
$208.93
Typical High
$208.93
Denver HMP
Setting
Facility
Modifier
None
Typical Low
$199.53
Median
$208.93
Typical High
$302.00
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$158.49
Median
$234.42
Typical High
$416.87
Select Health
Setting
Facility
Modifier
None
Typical Low
$208.93
Median
$389.05
Typical High
$446.68
Select Health
Setting
Professional
Modifier
None
Typical Low
$147.91
Median
$147.91
Typical High
$208.93
United
Setting
Facility
Modifier
None
Typical Low
$208.93
Median
$208.93
Typical High
$208.93
United
Setting
Professional
Modifier
None
Typical Low
$208.93
Median
$208.93
Typical High
$208.93
4 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$104.71
Median
$104.71
Typical High
$208.93
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$42.66
Median
$42.66
Typical High
$83.18
Aetna
Setting
Professional
Modifier
55 · Aftercare only
Typical Low
$31.62
Median
$31.62
Typical High
$61.66
Aetna
Setting
Professional
Modifier
56 · Pre-op care only
Typical Low
$20.89
Median
$20.89
Typical High
$41.69

Where Colorado sits

The same service costs 1.6 times more in Arizona than in New Jersey. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Colorado· 3rd of 51

$263

AZ $339NJ $209

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.