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Definitive Drug Test, 15-21 Drug Classes

Missouri rates for HCPCS G0482

Drug test(s), definitive, utilizing (1) drug identification methods able to identify individual drugs and distinguish between structural isomers (but not necessarily stereoisomers), including, but not limited to, GC/MS (any type, single or tandem) and LC/MS (any type, single or tandem and excluding immunoassays (e.g., IA, EIA, ELISA, EMIT, FPIA) and enzymatic methods (e.g., alcohol dehydrogenase)), (2) stable isotope or other universally recognized internal standards in all samples (e.g., to control for matrix effects, interferences and variations in signal strength), and (3) method or drug-specific calibration and matrix-matched quality control material (e.g., to control for instrument variations and mass spectral drift); qualitative or quantitative, all sources, includes specimen validity testing, per day; 15-21 drug class(es), including metabolite(s) if performed

Rates data updated July 2026.

How much does Definitive Drug Test, 15-21 Drug Classes cost?

$200

Typical negotiated rate. In Missouri, July 2026.

Insurers have agreed to pay about $200 for this service. The price depends on where it is billed: about $174 from a physician practice, and about $295 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$174$100 to $224
FacilityA hospital or hospital-owned outpatient department$295$200 to $347

How much rates vary

Facilitymedian $295 · 10th to 90th $178 to $457Professionalmedian $174 · 10th to 90th $46 to $263
$50$100$200$500$1Kfacility $295professional $174

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$194.98
Median
$331.13
Typical High
$389.05
Aetna
Setting
Professional
Modifier
Global
Typical Low
$169.82
Median
$194.98
Typical High
$331.13
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$199.53
Median
$199.53
Typical High
$691.83
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$45.71
Median
$138.04
Typical High
$251.19
Cigna
Setting
Facility
Modifier
Global
Typical Low
$112.20
Median
$380.19
Typical High
$851.14
Cigna
Setting
Professional
Modifier
Global
Typical Low
$60.26
Median
$60.26
Typical High
$60.26
Medica
Setting
Facility
Modifier
Global
Typical Low
$169.82
Median
$275.42
Typical High
$933.25
Medica
Setting
Professional
Modifier
Global
Typical Low
$83.18
Median
$100.00
Typical High
$208.93
United
Setting
Facility
Modifier
Global
Typical Low
$70.79
Median
$199.53
Typical High
$239.88
United
Setting
Professional
Modifier
Global
Typical Low
$83.18
Median
$100.00
Typical High
$239.88

Where Missouri sits

The same service costs 1.9 times more in Alaska than in Georgia. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 18th of 51

$200

AK $257GA $132

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.