Definitive Drug Test, 8-14 Drug Classes

South Carolina rates for HCPCS G0481

Drug test(s), definitive, utilizing (1) drug identification methods able to identify individual drugs and distinguish between structural isomers (but not necessarily stereoisomers), including, but not limited to, GC/MS (any type, single or tandem) and LC/MS (any type, single or tandem and excluding immunoassays (e.g., IA, EIA, ELISA, EMIT, FPIA) and enzymatic methods (e.g., alcohol dehydrogenase)), (2) stable isotope or other universally recognized internal standards in all samples (e.g., to control for matrix effects, interferences and variations in signal strength), and (3) method or drug-specific calibration and matrix-matched quality control material (e.g., to control for instrument variations and mass spectral drift); qualitative or quantitative, all sources, includes specimen validity testing, per day; 8-14 drug class(es), including metabolite(s) if performed

Rates data updated July 2026.

How much does Definitive Drug Test, 8-14 Drug Classes cost?

$219

Typical negotiated rate. In South Carolina, July 2026.

Insurers have agreed to pay about $219 for this service. The price depends on where it is billed: about $112 from a physician practice, and about $288 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed by	Who charges it	Typical	Range
Physician practiceA doctor's office, clinic or independent provider	A doctor's office, clinic or independent provider	$112	$89.13 to $166
FacilityA hospital or hospital-owned outpatient department	A hospital or hospital-owned outpatient department	$288	$186 to $468

How much rates vary

Facilitymedian $288 · 10th to 90th $52 to $562Professionalmedian $112 · 10th to 90th $76 to $447

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier	Facility/Professional	Modifier	Typical Low	Median	Typical High
Aetna Setting Facility Modifier Global Typical Low $52.48 Median $380.19 Typical High $562.34	Facility	Global	$52.48	$380.19	$562.34
Aetna Setting Professional Modifier Global Typical Low $75.86 Median $109.65 Typical High $446.68	Professional	Global	$75.86	$109.65	$446.68
BCBS Setting Facility Modifier Global Typical Low $954.99 Median $954.99 Typical High $1,023.29	Facility	Global	$954.99	$954.99	$1,023.29
BCBS Setting Professional Modifier Global Typical Low $112.20 Median $154.88 Typical High $218.78	Professional	Global	$112.20	$154.88	$218.78
Cigna Setting Facility Modifier Global Typical Low $204.17 Median $467.74 Typical High $891.25	Facility	Global	$204.17	$467.74	$891.25
Cigna Setting Professional Modifier Global Typical Low $83.18 Median $83.18 Typical High $162.18	Professional	Global	$83.18	$83.18	$162.18
Medcost Setting Facility Modifier Global Typical Low $117.49 Median $141.25 Typical High $208.93	Facility	Global	$117.49	$141.25	$208.93
United Setting Facility Modifier Global Typical Low $77.62 Median $154.88 Typical High $186.21	Facility	Global	$77.62	$154.88	$186.21
United Setting Professional Modifier Global Typical Low $61.66 Median $87.10 Typical High $186.21	Professional	Global	$61.66	$87.10	$186.21

Where South Carolina sits

The same service costs 1.9 times more in South Carolina than in Nevada. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Carolina· 1st of 51

$219

SC $219NV $112

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.