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Hepatitis B Vaccine For Adults, Boosted Formula

Florida rates for HCPCS 90739 · Heplisav-B

The hepatitis B vaccine prepared for adults with an added ingredient that strengthens the immune response, given as an injection into the muscle of the upper arm. Hepatitis B is a virus that attacks the liver and can cause long-term liver damage, and the vaccine trains the immune system to fight it off. The short course completes the series in fewer doses than the standard adult vaccine, though some people, such as those on dialysis, are given a longer four-dose course.

Rates data updated July 2026.

How much does Heplisav-B cost?

$178

Typical negotiated rate. In Florida, July 2026.

Insurers have agreed to pay about $178 for this service. The price depends on where it is billed: about $178 from a physician practice, and about $209 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$178$158 to $178
FacilityA hospital or hospital-owned outpatient department$209$178 to $468

How much rates vary

Facilitymedian $209 · 10th to 90th $178 to $692Professionalmedian $178 · 10th to 90th $115 to $200
$100$200$500$1K$2Kfacility $209professional $178

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$177.83
Median
$257.04
Typical High
$691.83
Aetna
Setting
Professional
Modifier
Global
Typical Low
$114.82
Median
$177.83
Typical High
$199.53
Ambetter
Setting
Professional
Modifier
Global
Typical Low
$151.36
Median
$263.03
Typical High
$302.00
AvMed
Setting
Professional
Modifier
Global
Typical Low
$169.82
Median
$177.83
Typical High
$177.83
Cigna
Setting
Facility
Modifier
Global
Typical Low
$213.80
Median
$275.42
Typical High
$363.08
Cigna
Setting
Professional
Modifier
Global
Typical Low
$186.21
Median
$186.21
Typical High
$186.21
Florida Blue
Setting
Facility
Modifier
Global
Typical Low
$177.83
Median
$177.83
Typical High
$177.83
Florida Blue
Setting
Professional
Modifier
Global
Typical Low
$158.49
Median
$158.49
Typical High
$177.83
United
Setting
Facility
Modifier
Global
Typical Low
$177.83
Median
$177.83
Typical High
$316.23
United
Setting
Professional
Modifier
Global
Typical Low
$154.88
Median
$154.88
Typical High
$199.53
Wellpoint
Setting
Professional
Modifier
Global
Typical Low
$154.88
Median
$177.83
Typical High
$177.83

Where Florida sits

The same service costs 1.7 times more in Ohio than in Maine. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Florida· 48th of 51

$178

OH $295ME $178

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.