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PCV20 Pneumococcal Vaccine Injection

Missouri rates for HCPCS 90677 · Prevnar 20

This is an injection of a vaccine that protects against 20 different strains of the bacteria that cause pneumococcal disease, including pneumonia, meningitis, and bloodstream infections. It is given as a shot into a muscle, usually the upper arm, and is recommended for many adults and some children to lower the risk of serious pneumococcal illness. A single dose is typically enough to update protection to the newer, broader-coverage version of the vaccine.

Rates data updated October 2026.

How much does Prevnar 20 (pneumococcal 20-valent conjugate vaccine) cost?

$355

Typical negotiated rate. In Missouri, October 2026.

Insurers have agreed to pay about $355 for this service. The price depends on where it is billed: about $355 from a physician practice, and about $427 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$355$331 to $380
FacilityA hospital or hospital-owned outpatient department$427$339 to $661

How much rates vary

Facilitymedian $427 · 10th to 90th $302 to $1,096Professionalmedian $355 · 10th to 90th $316 to $380
$500$1Kfacility $427professional $355

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$338.84
Median
$363.08
Typical High
$660.69
Aetna
Setting
Professional
Modifier
None
Typical Low
$338.84
Median
$338.84
Typical High
$512.86
Ambetter
Setting
Professional
Modifier
None
Typical Low
$263.03
Median
$316.23
Typical High
$346.74
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$331.13
Median
$457.09
Typical High
$1,096.48
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$323.59
Median
$380.19
Typical High
$380.19
Cigna
Setting
Facility
Modifier
None
Typical Low
$380.19
Median
$588.84
Typical High
$660.69
Cigna
Setting
Professional
Modifier
None
Typical Low
$354.81
Median
$354.81
Typical High
$354.81
Medica
Setting
Facility
Modifier
None
Typical Low
$295.12
Median
$331.13
Typical High
$1,174.90
Medica
Setting
Professional
Modifier
None
Typical Low
$275.42
Median
$323.59
Typical High
$331.13
United
Setting
Facility
Modifier
None
Typical Low
$331.13
Median
$331.13
Typical High
$331.13
United
Setting
Professional
Modifier
None
Typical Low
$316.23
Median
$354.81
Typical High
$389.05
4 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$169.82
Median
$169.82
Typical High
$177.83
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$67.61
Median
$67.61
Typical High
$72.44
Aetna
Setting
Professional
Modifier
55 · Aftercare only
Typical Low
$51.29
Median
$51.29
Typical High
$53.70
Aetna
Setting
Professional
Modifier
56 · Pre-op care only
Typical Low
$33.88
Median
$33.88
Typical High
$36.31

Where Missouri sits

The same service costs 2.9 times more in Arizona than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 18th of 51

$355

AZ $468AL $162

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.