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Separating Selected Cells From A Tissue Sample

Missouri rates for HCPCS 88381

A laboratory preparation step in which a very small, specific group of cells is separated out from a tissue sample viewed under a microscope. Isolating those cells means that a later test measures only the area of interest instead of the surrounding normal tissue, which makes the result more reliable. It produces material for further testing rather than a diagnosis of its own.

Rates data updated October 2026.

How much does Separating Selected Cells From A Tissue Sample cost?

$224

Typical negotiated rate. In Missouri, October 2026.

Insurers have agreed to pay about $224 for this service. The price depends on where it is billed: about $200 from a physician practice, and about $324 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$200$166 to $676
FacilityA hospital or hospital-owned outpatient department$324$229 to $407

How much rates vary

Facilitymedian $324 · 10th to 90th $148 to $891Professionalmedian $200 · 10th to 90th $95 to $1,349
$100$200$500$1Kfacility $324professional $200

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$131.83
Median
$165.96
Typical High
$190.55
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$134.90
Median
$190.55
Typical High
$416.87
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$18.62
Median
$22.39
Typical High
$52.48
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$134.90
Median
$165.96
Typical High
$204.17
Anthem BCBS
Setting
Professional
Modifier
None (both parts)
Typical Low
$64.57
Median
$181.97
Typical High
$676.08
Anthem BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$20.42
Median
$52.48
Typical High
$194.98
Anthem BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$44.67
Median
$131.83
Typical High
$562.34
BCBS Kansas City
Setting
Facility
Modifier
None
Typical Low
$229.09
Median
$295.12
Typical High
$562.34
BCBS Kansas City
Setting
Professional
Modifier
None (both parts)
Typical Low
$169.82
Median
$194.98
Typical High
$346.74
Cigna
Setting
Facility
Modifier
None
Typical Low
$123.03
Median
$363.08
Typical High
$426.58
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$74.13
Median
$100.00
Typical High
$234.42
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$11.22
Median
$12.88
Typical High
$72.44
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$61.66
Median
$85.11
Typical High
$199.53
Medica
Setting
Facility
Modifier
None
Typical Low
$199.53
Median
$316.23
Typical High
$891.25
Medica
Setting
Professional
Modifier
None (both parts)
Typical Low
$151.36
Median
$1,348.96
Typical High
$1,348.96
Medica
Setting
Professional
Modifier
26 · Professional part
Typical Low
$25.70
Median
$316.23
Typical High
$316.23
Medica
Setting
Professional
Modifier
TC · Technical part
Typical Low
$104.71
Median
$1,202.26
Typical High
$1,202.26
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$109.65
Median
$181.97
Typical High
$478.63
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$13.80
Median
$25.70
Typical High
$58.88
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$93.33
Median
$151.36
Typical High
$398.11

Where Missouri sits

The same service costs 6.5 times more in North Dakota than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 21st of 51

$224

ND $363AL $56.23

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.