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Separating Selected Cells From A Tissue Sample

Minnesota rates for HCPCS 88381

A laboratory preparation step in which a very small, specific group of cells is separated out from a tissue sample viewed under a microscope. Isolating those cells means that a later test measures only the area of interest instead of the surrounding normal tissue, which makes the result more reliable. It produces material for further testing rather than a diagnosis of its own.

Rates data updated October 2026.

How much does Separating Selected Cells From A Tissue Sample cost?

$288

Typical negotiated rate. In Minnesota, October 2026.

Insurers have agreed to pay about $288 for this service. The price depends on where it is billed: about $331 from a physician practice, and about $182 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$331$251 to $490
FacilityA hospital or hospital-owned outpatient department$182$132 to $479

How much rates vary

Facilitymedian $182 · 10th to 90th $132 to $759Professionalmedian $331 · 10th to 90th $182 to $676
$50$100$200$500$1K$2Kfacility $182professional $331

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$131.83
Median
$181.97
Typical High
$181.97
Aetna
Setting
Facility
Modifier
26 · Professional part
Typical Low
$20.42
Median
$20.42
Typical High
$20.42
Aetna
Setting
Facility
Modifier
TC · Technical part
Typical Low
$158.49
Median
$158.49
Typical High
$158.49
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$181.97
Median
$181.97
Typical High
$186.21
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$20.42
Median
$20.42
Typical High
$25.70
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$158.49
Median
$158.49
Typical High
$158.49
BCBS Minnesota
Setting
Facility
Modifier
None
Typical Low
$162.18
Median
$213.80
Typical High
$426.58
BCBS Minnesota
Setting
Professional
Modifier
None (both parts)
Typical Low
$263.03
Median
$446.68
Typical High
$707.95
BCBS Minnesota
Setting
Professional
Modifier
26 · Professional part
Typical Low
$30.90
Median
$53.70
Typical High
$83.18
BCBS Minnesota
Setting
Professional
Modifier
TC · Technical part
Typical Low
$218.78
Median
$416.87
Typical High
$630.96
Cigna
Setting
Facility
Modifier
None
Typical Low
$436.52
Median
$676.08
Typical High
$1,995.26
Cigna
Setting
Facility
Modifier
26 · Professional part
Typical Low
$48.98
Median
$77.62
Typical High
$223.87
Cigna
Setting
Facility
Modifier
TC · Technical part
Typical Low
$380.19
Median
$602.56
Typical High
$1,778.28
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$263.03
Median
$288.40
Typical High
$380.19
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$29.51
Median
$32.36
Typical High
$43.65
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$229.09
Median
$251.19
Typical High
$338.84
Health Partners
Setting
Facility
Modifier
None
Typical Low
$398.11
Median
$660.69
Typical High
$1,548.82
Health Partners
Setting
Facility
Modifier
26 · Professional part
Typical Low
$45.71
Median
$74.13
Typical High
$177.83
Health Partners
Setting
Facility
Modifier
TC · Technical part
Typical Low
$354.81
Median
$575.44
Typical High
$1,380.38
Health Partners
Setting
Professional
Modifier
None (both parts)
Typical Low
$257.04
Median
$257.04
Typical High
$363.08
Health Partners
Setting
Professional
Modifier
26 · Professional part
Typical Low
$29.51
Median
$29.51
Typical High
$41.69
Health Partners
Setting
Professional
Modifier
TC · Technical part
Typical Low
$229.09
Median
$229.09
Typical High
$323.59
Medica
Setting
Facility
Modifier
None
Typical Low
$275.42
Median
$354.81
Typical High
$616.60
Medica
Setting
Professional
Modifier
None (both parts)
Typical Low
$109.65
Median
$380.19
Typical High
$1,348.96
Medica
Setting
Professional
Modifier
26 · Professional part
Typical Low
$25.70
Median
$67.61
Typical High
$316.23
Medica
Setting
Professional
Modifier
TC · Technical part
Typical Low
$93.33
Median
$331.13
Typical High
$1,202.26
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$109.65
Median
$223.87
Typical High
$537.03
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$15.49
Median
$46.77
Typical High
$75.86
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$93.33
Median
$194.98
Typical High
$457.09

Where Minnesota sits

The same service costs 6.5 times more in North Dakota than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Minnesota· 8th of 51

$288

ND $363AL $56.23

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.