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Separating Selected Cells From A Tissue Sample

Michigan rates for HCPCS 88381

A laboratory preparation step in which a very small, specific group of cells is separated out from a tissue sample viewed under a microscope. Isolating those cells means that a later test measures only the area of interest instead of the surrounding normal tissue, which makes the result more reliable. It produces material for further testing rather than a diagnosis of its own.

Rates data updated October 2026.

How much does Separating Selected Cells From A Tissue Sample cost?

$240

Typical negotiated rate. In Michigan, October 2026.

Insurers have agreed to pay about $240 for this service. The price depends on where it is billed: about $234 from a physician practice, and about $288 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$234$155 to $288
FacilityA hospital or hospital-owned outpatient department$288$204 to $372

How much rates vary

Facilitymedian $288 · 10th to 90th $170 to $490Professionalmedian $234 · 10th to 90th $34 to $309
$10$20$50$100$200$500facility $288professional $234

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$165.96
Median
$169.82
Typical High
$239.88
Aetna
Setting
Facility
Modifier
TC · Technical part
Typical Low
$147.91
Median
$154.88
Typical High
$323.59
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$165.96
Median
$190.55
Typical High
$213.80
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$20.89
Median
$22.39
Typical High
$28.18
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$144.54
Median
$165.96
Typical High
$165.96
Ambetter
Setting
Professional
Modifier
26 · Professional part
Typical Low
$21.88
Median
$21.88
Typical High
$21.88
BCBS Michigan
Setting
Facility
Modifier
None
Typical Low
$204.17
Median
$288.40
Typical High
$512.86
BCBS Michigan
Setting
Professional
Modifier
None (both parts)
Typical Low
$33.88
Median
$288.40
Typical High
$309.03
BCBS Michigan
Setting
Professional
Modifier
26 · Professional part
Typical Low
$36.31
Median
$36.31
Typical High
$36.31
BCBS Michigan
Setting
Professional
Modifier
TC · Technical part
Typical Low
$275.42
Median
$275.42
Typical High
$275.42
CareSource
Setting
Facility
Modifier
None
Typical Low
$194.98
Median
$194.98
Typical High
$194.98
CareSource
Setting
Professional
Modifier
None (both parts)
Typical Low
$21.38
Median
$173.78
Typical High
$234.42
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$70.79
Median
$102.33
Typical High
$331.13
Health Alliance Plan
Setting
Facility
Modifier
None
Typical Low
$74.13
Median
$407.38
Typical High
$457.09
Health Alliance Plan
Setting
Facility
Modifier
TC · Technical part
Typical Low
$154.88
Median
$208.93
Typical High
$323.59
Health Alliance Plan
Setting
Professional
Modifier
None (both parts)
Typical Low
$154.88
Median
$204.17
Typical High
$239.88
Health Alliance Plan
Setting
Professional
Modifier
26 · Professional part
Typical Low
$21.88
Median
$48.98
Typical High
$69.18
Health Alliance Plan
Setting
Professional
Modifier
TC · Technical part
Typical Low
$107.15
Median
$141.25
Typical High
$208.93
Priority Health
Setting
Professional
Modifier
None (both parts)
Typical Low
$70.79
Median
$91.20
Typical High
$263.03
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$109.65
Median
$173.78
Typical High
$257.04
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$15.49
Median
$36.31
Typical High
$63.10
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$93.33
Median
$125.89
Typical High
$218.78

Where Michigan sits

The same service costs 6.5 times more in North Dakota than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Michigan· 20th of 51

$240

ND $363AL $56.23

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.