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Separating Selected Cells From A Tissue Sample

Massachusetts rates for HCPCS 88381

A laboratory preparation step in which a very small, specific group of cells is separated out from a tissue sample viewed under a microscope. Isolating those cells means that a later test measures only the area of interest instead of the surrounding normal tissue, which makes the result more reliable. It produces material for further testing rather than a diagnosis of its own.

Rates data updated July 2026.

How much does Separating Selected Cells From A Tissue Sample cost?

$295

Typical negotiated rate. In Massachusetts, July 2026.

Insurers have agreed to pay about $295 for this service. Most negotiated rates run $186 to $468.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $295 · 10th to 90th $100 to $692
$50$100$200$500$1Kprofessional $295

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$186.21
Typical High
$794.33
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$15.49
Median
$35.48
Typical High
$181.97
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$58.88
Median
$138.04
Typical High
$616.60
AllWays Health Partners
Setting
Facility
Modifier
26 · Professional part
Typical Low
$239.88
Median
$239.88
Typical High
$239.88
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$158.49
Median
$295.12
Typical High
$1,348.96
AllWays Health Partners
Setting
Professional
Modifier
26 · Professional part
Typical Low
$23.44
Median
$48.98
Typical High
$331.13
AllWays Health Partners
Setting
Professional
Modifier
TC · Technical part
Typical Low
$125.89
Median
$257.04
Typical High
$1,202.26
BCBS
Setting
Professional
Modifier
Global
Typical Low
$245.47
Median
$416.87
Typical High
$562.34
BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$26.30
Median
$44.67
Typical High
$58.88
BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$144.54
Median
$144.54
Typical High
$208.93
Cigna
Setting
Professional
Modifier
Global
Typical Low
$77.62
Median
$213.80
Typical High
$346.74
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$11.75
Median
$22.91
Typical High
$81.28
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$64.57
Median
$190.55
Typical High
$316.23
Fallon Health
Setting
Professional
Modifier
Global
Typical Low
$27.54
Median
$223.87
Typical High
$371.54
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$229.09
Median
$398.11
Typical High
$537.03
Harvard Pilgrim
Setting
Professional
Modifier
26 · Professional part
Typical Low
$26.92
Median
$46.77
Typical High
$63.10
Harvard Pilgrim
Setting
Professional
Modifier
TC · Technical part
Typical Low
$199.53
Median
$346.74
Typical High
$489.78
Mass General Brigham
Setting
Facility
Modifier
26 · Professional part
Typical Low
$239.88
Median
$239.88
Typical High
$239.88
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$158.49
Median
$295.12
Typical High
$1,348.96
Mass General Brigham
Setting
Professional
Modifier
26 · Professional part
Typical Low
$23.44
Median
$48.98
Typical High
$331.13
Mass General Brigham
Setting
Professional
Modifier
TC · Technical part
Typical Low
$125.89
Median
$257.04
Typical High
$1,202.26
United
Setting
Professional
Modifier
Global
Typical Low
$162.18
Median
$288.40
Typical High
$562.34
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$23.99
Median
$40.74
Typical High
$72.44
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$125.89
Median
$234.42
Typical High
$501.19

Where Massachusetts sits

The same service costs 3.5 times more in Minnesota than in Florida. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Massachusetts· 6th of 51

$295

MN $427FL $123

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.