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Separating Selected Cells From A Tissue Sample

Illinois rates for HCPCS 88381

A laboratory preparation step in which a very small, specific group of cells is separated out from a tissue sample viewed under a microscope. Isolating those cells means that a later test measures only the area of interest instead of the surrounding normal tissue, which makes the result more reliable. It produces material for further testing rather than a diagnosis of its own.

Rates data updated October 2026.

How much does Separating Selected Cells From A Tissue Sample cost?

$195

Typical negotiated rate. In Illinois, October 2026.

Insurers have agreed to pay about $195 for this service. The price depends on where it is billed: about $174 from a physician practice, and about $437 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$174$37.15 to $257
FacilityA hospital or hospital-owned outpatient department$437$309 to $741

How much rates vary

Facilitymedian $437 · 10th to 90th $158 to $1,585Professionalmedian $174 · 10th to 90th $31 to $295
$50$100$200$500$1K$2K$5Kfacility $437professional $174

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$151.36
Median
$173.78
Typical High
$575.44
Aetna
Setting
Facility
Modifier
TC · Technical part
Typical Low
$141.25
Median
$281.84
Typical High
$562.34
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$162.18
Median
$173.78
Typical High
$190.55
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$19.05
Median
$19.50
Typical High
$23.99
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$141.25
Median
$154.88
Typical High
$165.96
Ambetter
Setting
Professional
Modifier
26 · Professional part
Typical Low
$30.20
Median
$30.20
Typical High
$30.20
BCBS Illinois
Setting
Facility
Modifier
None
Typical Low
$346.74
Median
$562.34
Typical High
$4,466.84
BCBS Illinois
Setting
Professional
Modifier
None (both parts)
Typical Low
$25.12
Median
$181.97
Typical High
$295.12
Cigna
Setting
Facility
Modifier
None
Typical Low
$144.54
Median
$331.13
Typical High
$741.31
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$87.10
Median
$158.49
Typical High
$263.03
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$10.96
Median
$30.20
Typical High
$48.98
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$75.86
Median
$117.49
Typical High
$229.09
Hally Health
Setting
Professional
Modifier
None
Typical Low
$208.93
Median
$288.40
Typical High
$524.81
Hally Health
Setting
Professional
Modifier
26 · Professional part
Typical Low
$26.30
Median
$34.67
Typical High
$83.18
Hally Health
Setting
Professional
Modifier
TC · Technical part
Typical Low
$173.78
Median
$245.47
Typical High
$426.58
Hally Health
Setting
Facility
Modifier
None
Typical Low
$100.00
Median
$100.00
Typical High
$100.00
Molina
Setting
Professional
Modifier
None (both parts)
Typical Low
$33.11
Median
$33.11
Typical High
$33.11
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$114.82
Median
$190.55
Typical High
$338.84
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$16.22
Median
$30.90
Typical High
$60.26
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$97.72
Median
$158.49
Typical High
$288.40

Where Illinois sits

The same service costs 6.5 times more in North Dakota than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Illinois· 26th of 51

$195

ND $363AL $56.23

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.