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Separating Selected Cells From A Tissue Sample

Colorado rates for HCPCS 88381

A laboratory preparation step in which a very small, specific group of cells is separated out from a tissue sample viewed under a microscope. Isolating those cells means that a later test measures only the area of interest instead of the surrounding normal tissue, which makes the result more reliable. It produces material for further testing rather than a diagnosis of its own.

Rates data updated October 2026.

How much does Separating Selected Cells From A Tissue Sample cost?

$257

Typical negotiated rate. In Colorado, October 2026.

Insurers have agreed to pay about $257 for this service. The price depends on where it is billed: about $245 from a physician practice, and about $407 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$245$151 to $417
FacilityA hospital or hospital-owned outpatient department$407$195 to $513

How much rates vary

Facilitymedian $407 · 10th to 90th $107 to $813Professionalmedian $245 · 10th to 90th $95 to $676
$100$200$500facility $407professional $245

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$151.36
Median
$151.36
Typical High
$151.36
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$123.03
Median
$151.36
Typical High
$234.42
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$15.85
Median
$16.98
Typical High
$57.54
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$109.65
Median
$131.83
Typical High
$204.17
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$407.38
Median
$478.63
Typical High
$851.14
Anthem BCBS
Setting
Professional
Modifier
None (both parts)
Typical Low
$213.80
Median
$416.87
Typical High
$724.44
Anthem BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$23.99
Median
$45.71
Typical High
$81.28
Anthem BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$190.55
Median
$371.54
Typical High
$645.65
Cigna
Setting
Facility
Modifier
None
Typical Low
$97.72
Median
$190.55
Typical High
$524.81
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$85.11
Median
$97.72
Typical High
$323.59
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$10.96
Median
$25.12
Typical High
$72.44
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$61.66
Median
$87.10
Typical High
$245.47
Denver HMP
Setting
Facility
Modifier
None
Typical Low
$138.04
Median
$213.80
Typical High
$275.42
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$239.88
Median
$281.84
Typical High
$812.83
Kaiser Permanente
Setting
Professional
Modifier
26 · Professional part
Typical Low
$26.92
Median
$32.36
Typical High
$89.13
Kaiser Permanente
Setting
Professional
Modifier
TC · Technical part
Typical Low
$208.93
Median
$251.19
Typical High
$724.44
Select Health
Setting
Facility
Modifier
None
Typical Low
$199.53
Median
$363.08
Typical High
$416.87
Select Health
Setting
Professional
Modifier
None (both parts)
Typical Low
$165.96
Median
$173.78
Typical High
$489.78
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$109.65
Median
$125.89
Typical High
$380.19
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$13.49
Median
$30.90
Typical High
$58.88
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$77.62
Median
$107.15
Typical High
$316.23

Where Colorado sits

The same service costs 6.5 times more in North Dakota than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Colorado· 17th of 51

$257

ND $363AL $56.23

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.