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Separating Selected Cells From A Tissue Sample

Colorado rates for HCPCS 88381

A laboratory preparation step in which a very small, specific group of cells is separated out from a tissue sample viewed under a microscope. Isolating those cells means that a later test measures only the area of interest instead of the surrounding normal tissue, which makes the result more reliable. It produces material for further testing rather than a diagnosis of its own.

Rates data updated July 2026.

How much does Separating Selected Cells From A Tissue Sample cost?

$162

Typical negotiated rate. In Colorado, July 2026.

Insurers have agreed to pay about $162 for this service. Most negotiated rates run $123 to $234.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $162 · 10th to 90th $76 to $347
$100.0$200.0$500.0professional $162

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
Global
Typical Low
$75.86
Median
$151.36
Typical High
$331.13
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$14.79
Median
$17.78
Typical High
$42.66
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$60.26
Median
$131.83
Typical High
$204.17
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$213.80
Median
$213.80
Typical High
$363.08
Anthem BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$23.99
Median
$23.99
Typical High
$45.71
Anthem BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$190.55
Median
$190.55
Typical High
$323.59
Cigna
Setting
Professional
Modifier
Global
Typical Low
$85.11
Median
$128.82
Typical High
$331.13
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$10.96
Median
$25.12
Typical High
$66.07
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$61.66
Median
$114.82
Typical High
$275.42
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$275.42
Median
$275.42
Typical High
$275.42
Kaiser Permanente
Setting
Professional
Modifier
26 · Professional part
Typical Low
$31.62
Median
$31.62
Typical High
$31.62
Kaiser Permanente
Setting
Professional
Modifier
TC · Technical part
Typical Low
$245.47
Median
$245.47
Typical High
$245.47
Select Health
Setting
Professional
Modifier
Global
Typical Low
$173.78
Median
$245.47
Typical High
$489.78
Select Health
Setting
Professional
Modifier
26 · Professional part
Typical Low
$21.38
Median
$27.54
Typical High
$56.23
Select Health
Setting
Professional
Modifier
TC · Technical part
Typical Low
$151.36
Median
$218.78
Typical High
$436.52
United
Setting
Professional
Modifier
Global
Typical Low
$109.65
Median
$125.89
Typical High
$371.54
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$13.49
Median
$32.36
Typical High
$95.50
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$77.62
Median
$107.15
Typical High
$295.12

Where Colorado sits

The same service costs 3.5 times more in Minnesota than in Florida. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Colorado $162 · 31st of 51
MN $427FL $123

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.