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In Situ Hybridization Analysis of Tissue

Virginia rates for HCPCS 88373

A laboratory analysis in which a piece of tissue is treated with a labeled probe that sticks to one specific stretch of genetic material, and the amount present is then measured. It is performed on a sample already being examined by a pathologist and is reported in addition to that examination.

Rates data updated October 2026.

How much does In Situ Hybridization Analysis of Tissue cost?

$58.88

Typical negotiated rate. In Virginia, October 2026.

Insurers have agreed to pay about $58.88 for this service. The price depends on where it is billed: about $51.29 from a physician practice, and about $69.18 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$51.29$32.36 to $69.18
FacilityA hospital or hospital-owned outpatient department$69.18$43.65 to $112

How much rates vary

Facilitymedian $69 · 10th to 90th $28 to $245Professionalmedian $51 · 10th to 90th $32 to $98
$20$100$500$2K$10Kfacility $69professional $51

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$60.26
Median
$60.26
Typical High
$64.57
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$54.95
Median
$60.26
Typical High
$64.57
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$20.42
Median
$20.42
Typical High
$23.99
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$35.48
Median
$40.74
Typical High
$40.74
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$177.83
Median
$229.09
Typical High
$288.40
Anthem BCBS
Setting
Professional
Modifier
None (both parts)
Typical Low
$32.36
Median
$32.36
Typical High
$50.12
Anthem BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$11.48
Median
$11.48
Typical High
$18.62
Anthem BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$20.42
Median
$20.42
Typical High
$32.36
CareFirst
Setting
Professional
Modifier
None (both parts)
Typical Low
$22.91
Median
$58.88
Typical High
$69.18
CareFirst
Setting
Professional
Modifier
26 · Professional part
Typical Low
$20.89
Median
$20.89
Typical High
$28.84
CareFirst
Setting
Professional
Modifier
TC · Technical part
Typical Low
$42.66
Median
$42.66
Typical High
$53.70
Cigna
Setting
Facility
Modifier
None
Typical Low
$43.65
Median
$87.10
Typical High
$158.49
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$28.84
Median
$38.02
Typical High
$112.20
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$10.72
Median
$12.59
Typical High
$38.90
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$18.20
Median
$25.70
Typical High
$75.86
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$69.18
Median
$72.44
Typical High
$87.10
Medcost
Setting
Facility
Modifier
None
Typical Low
$79.43
Median
$79.43
Typical High
$134.90
Medcost
Setting
Professional
Modifier
None (both parts)
Typical Low
$20.42
Median
$20.42
Typical High
$85.11
Sentara
Setting
Facility
Modifier
None
Typical Low
$23.99
Median
$58.88
Typical High
$194.98
Sentara
Setting
Professional
Modifier
None (both parts)
Typical Low
$31.62
Median
$69.18
Typical High
$128.82
Sentara
Setting
Professional
Modifier
26 · Professional part
Typical Low
$23.99
Median
$27.54
Typical High
$54.95
Sentara
Setting
Professional
Modifier
TC · Technical part
Typical Low
$44.67
Median
$50.12
Typical High
$107.15
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$44.67
Median
$75.86
Typical High
$151.36
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$14.79
Median
$27.54
Typical High
$54.95
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$28.18
Median
$46.77
Typical High
$95.50
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$27.54
Median
$30.20
Typical High
$31.62
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$10.96
Median
$12.02
Typical High
$12.88

Where Virginia sits

The same service costs 4.4 times more in Alaska than in Texas. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Virginia· 42nd of 51

$58.88

AK $182TX $41.69

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.