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In Situ Hybridization Analysis of Tissue

South Dakota rates for HCPCS 88373

A laboratory analysis in which a piece of tissue is treated with a labeled probe that sticks to one specific stretch of genetic material, and the amount present is then measured. It is performed on a sample already being examined by a pathologist and is reported in addition to that examination.

Rates data updated October 2026.

How much does In Situ Hybridization Analysis of Tissue cost?

$129

Typical negotiated rate. In South Dakota, October 2026.

Insurers have agreed to pay about $129 for this service. The price depends on where it is billed: about $129 from a physician practice, and about $75.86 from a hospital or other facility.

Few insurers publish rates for this combination, so treat this figure as a rough guide.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$129$105 to $145
FacilityA hospital or hospital-owned outpatient department$75.86$72.44 to $145

How much rates vary

Facilitymedian $76 · 10th to 90th $65 to $145Professionalmedian $129 · 10th to 90th $52 to $158
$50$100$200facility $76professional $129

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$52.48
Median
$52.48
Typical High
$52.48
Aetna
Setting
Professional
Modifier
None
Typical Low
$52.48
Median
$52.48
Typical High
$52.48
Cigna
Setting
Facility
Modifier
None
Typical Low
$144.54
Median
$144.54
Typical High
$144.54
Cigna
Setting
Professional
Modifier
None
Typical Low
$109.65
Median
$128.82
Typical High
$144.54
Medica
Setting
Facility
Modifier
None
Typical Low
$64.57
Median
$75.86
Typical High
$75.86
Medica
Setting
Professional
Modifier
None
Typical Low
$44.67
Median
$128.82
Typical High
$436.52
Midlands
Setting
Professional
Modifier
None
Typical Low
$114.82
Median
$128.82
Typical High
$128.82
Sanford Health Plan
Setting
Professional
Modifier
None
Typical Low
$91.20
Median
$112.20
Typical High
$128.82
United
Setting
Professional
Modifier
None
Typical Low
$40.74
Median
$44.67
Typical High
$158.49
Wellmark
Setting
Professional
Modifier
None
Typical Low
$131.83
Median
$144.54
Typical High
$144.54

Where South Dakota sits

The same service costs 4.4 times more in Alaska than in Texas. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Dakota· 3rd of 51

$129

AK $182TX $41.69

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.