go back

In Situ Hybridization Analysis of Tissue

South Dakota rates for HCPCS 88373

A laboratory analysis in which a piece of tissue is treated with a labeled probe that sticks to one specific stretch of genetic material, and the amount present is then measured. It is performed on a sample already being examined by a pathologist and is reported in addition to that examination.

Rates data updated July 2026.

How much does In Situ Hybridization Analysis of Tissue cost?

$112

Typical negotiated rate. In South Dakota, July 2026.

Insurers have agreed to pay about $112 for this service. Most negotiated rates run $52.48 to $129.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $112 · 10th to 90th $52 to $145
$50.0$100.0$200.0professional $112

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
Global
Typical Low
$52.48
Median
$52.48
Typical High
$52.48
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$19.95
Median
$19.95
Typical High
$19.95
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$33.11
Median
$33.11
Typical High
$33.11
Cigna
Setting
Professional
Modifier
Global
Typical Low
$87.10
Median
$120.23
Typical High
$177.83
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$31.62
Median
$44.67
Typical High
$66.07
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$54.95
Median
$75.86
Typical High
$114.82
Medica
Setting
Professional
Modifier
Global
Typical Low
$44.67
Median
$128.82
Typical High
$436.52
Medica
Setting
Professional
Modifier
26 · Professional part
Typical Low
$16.60
Median
$51.29
Typical High
$158.49
Medica
Setting
Professional
Modifier
TC · Technical part
Typical Low
$28.18
Median
$93.33
Typical High
$281.84
Midlands
Setting
Professional
Modifier
Global
Typical Low
$114.82
Median
$128.82
Typical High
$128.82
Midlands
Setting
Professional
Modifier
26 · Professional part
Typical Low
$42.66
Median
$50.12
Typical High
$50.12
Midlands
Setting
Professional
Modifier
TC · Technical part
Typical Low
$72.44
Median
$79.43
Typical High
$79.43
Sanford Health Plan
Setting
Professional
Modifier
Global
Typical Low
$91.20
Median
$120.23
Typical High
$134.90
Sanford Health Plan
Setting
Professional
Modifier
26 · Professional part
Typical Low
$33.88
Median
$44.67
Typical High
$47.86
Sanford Health Plan
Setting
Professional
Modifier
TC · Technical part
Typical Low
$58.88
Median
$77.62
Typical High
$85.11
United
Setting
Professional
Modifier
Global
Typical Low
$40.74
Median
$44.67
Typical High
$158.49
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$14.45
Median
$16.60
Typical High
$57.54
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$25.70
Median
$28.18
Typical High
$102.33
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$112.20
Median
$138.04
Typical High
$144.54
Wellmark
Setting
Professional
Modifier
26 · Professional part
Typical Low
$41.69
Median
$51.29
Typical High
$53.70
Wellmark
Setting
Professional
Modifier
TC · Technical part
Typical Low
$70.79
Median
$87.10
Typical High
$91.20

Where South Dakota sits

The same service costs 3.5 times more in Minnesota than in Delaware. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

South Dakota $112 · 5th of 51
MN $145DE $41.69

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.