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In Situ Hybridization Analysis of Tissue

South Carolina rates for HCPCS 88373

A laboratory analysis in which a piece of tissue is treated with a labeled probe that sticks to one specific stretch of genetic material, and the amount present is then measured. It is performed on a sample already being examined by a pathologist and is reported in addition to that examination.

Rates data updated October 2026.

How much does In Situ Hybridization Analysis of Tissue cost?

$63.10

Typical negotiated rate. In South Carolina, October 2026.

Insurers have agreed to pay about $63.10 for this service. The price depends on where it is billed: about $60.26 from a physician practice, and about $83.18 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$60.26$37.15 to $85.11
FacilityA hospital or hospital-owned outpatient department$83.18$70.79 to $209

How much rates vary

Facilitymedian $83 · 10th to 90th $50 to $245Professionalmedian $60 · 10th to 90th $30 to $138
$50$100$200facility $83professional $60

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$50.12
Median
$50.12
Typical High
$50.12
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$50.12
Median
$50.12
Typical High
$53.70
BCBS South Carolina
Setting
Facility
Modifier
None
Typical Low
$380.19
Median
$380.19
Typical High
$389.05
BCBS South Carolina
Setting
Professional
Modifier
None (both parts)
Typical Low
$60.26
Median
$107.15
Typical High
$138.04
BCBS South Carolina
Setting
Professional
Modifier
26 · Professional part
Typical Low
$23.44
Median
$40.74
Typical High
$52.48
BCBS South Carolina
Setting
Professional
Modifier
TC · Technical part
Typical Low
$36.31
Median
$66.07
Typical High
$85.11
Cigna
Setting
Facility
Modifier
None
Typical Low
$75.86
Median
$102.33
Typical High
$245.47
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$28.84
Median
$29.51
Typical High
$85.11
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$10.23
Median
$10.96
Typical High
$30.90
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$18.20
Median
$18.62
Typical High
$53.70
Medcost
Setting
Facility
Modifier
None
Typical Low
$50.12
Median
$60.26
Typical High
$181.97
Medcost
Setting
Professional
Modifier
None (both parts)
Typical Low
$77.62
Median
$85.11
Typical High
$85.11
Medcost
Setting
Professional
Modifier
26 · Professional part
Typical Low
$30.90
Median
$30.90
Typical High
$42.66
Medcost
Setting
Professional
Modifier
TC · Technical part
Typical Low
$53.70
Median
$53.70
Typical High
$70.79
Molina
Setting
Professional
Modifier
None (both parts)
Typical Low
$26.30
Median
$42.66
Typical High
$81.28
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$33.88
Median
$69.18
Typical High
$147.91
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$12.30
Median
$26.92
Typical High
$54.95
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$21.38
Median
$42.66
Typical High
$95.50
5 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Medcost
Setting
Professional
Modifier
51 · Multiple procedures
Typical Low
$42.66
Median
$42.66
Typical High
$48.98
Medcost
Setting
Professional
Modifier
80 · Assistant surgeon
Typical Low
$16.98
Median
$16.98
Typical High
$19.50
Medcost
Setting
Professional
Modifier
81 · Minimal assistant surgeon
Typical Low
$11.75
Median
$11.75
Typical High
$13.49
Medcost
Setting
Professional
Modifier
82 · Assistant surgeon, no resident
Typical Low
$11.75
Median
$11.75
Typical High
$13.49
Medcost
Setting
Professional
Modifier
AS · PA/NP assist
Typical Low
$11.75
Median
$11.75
Typical High
$13.49

Where South Carolina sits

The same service costs 4.4 times more in Alaska than in Texas. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Carolina· 34th of 51

$63.10

AK $182TX $41.69

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.